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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CENPF
All Species:
8.48
Human Site:
T1633
Identified Species:
15.56
UniProt:
P49454
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49454
NP_057427.3
3210
367764
T1633
S
L
Q
E
E
N
L
T
R
K
E
T
P
S
A
Chimpanzee
Pan troglodytes
XP_001171549
3114
357698
T1537
S
L
Q
E
E
N
L
T
R
K
E
T
P
S
A
Rhesus Macaque
Macaca mulatta
XP_001105956
3113
357422
T1536
S
L
L
E
E
N
L
T
K
K
E
M
P
S
A
Dog
Lupus familis
XP_852813
1449
166096
L50
L
I
Q
E
K
E
H
L
M
L
M
E
T
K
Q
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510329
2965
340022
K1519
C
V
E
S
S
F
Y
K
N
L
F
D
Q
T
G
Chicken
Gallus gallus
O42184
1433
161009
P33
P
A
S
V
A
T
A
P
A
E
K
A
P
S
S
Frog
Xenopus laevis
P85120
2058
236320
K659
S
I
K
I
V
E
E
K
M
Q
G
L
E
K
E
Zebra Danio
Brachydanio rerio
XP_002665261
2708
311087
L1309
R
S
V
L
V
A
E
L
E
S
L
R
V
I
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VJE5
1690
189046
F291
T
V
D
D
I
R
Y
F
E
C
K
P
K
Y
G
Honey Bee
Apis mellifera
XP_001120388
2064
240016
L665
L
Q
Q
N
M
Q
N
L
K
T
E
N
G
E
L
Nematode Worm
Caenorhab. elegans
P02566
1966
225108
K567
G
K
H
P
N
F
E
K
P
K
P
P
K
G
K
Sea Urchin
Strong. purpuratus
XP_796801
3636
416057
A1846
V
K
F
S
L
E
E
A
R
S
D
L
S
Q
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P25386
1790
206434
G391
P
V
N
S
T
A
N
G
G
P
I
K
L
I
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.8
91.4
32.8
N.A.
N.A.
N.A.
N.A.
50.5
20.4
21.5
31.3
N.A.
21.3
22.9
20.1
22
Protein Similarity:
100
96.4
93.8
39.1
N.A.
N.A.
N.A.
N.A.
67.5
32.4
38.6
51.2
N.A.
35.2
41.3
36.4
43.7
P-Site Identity:
100
100
80
13.3
N.A.
N.A.
N.A.
N.A.
0
13.3
6.6
0
N.A.
0
13.3
6.6
13.3
P-Site Similarity:
100
100
86.6
26.6
N.A.
N.A.
N.A.
N.A.
20
33.3
26.6
0
N.A.
26.6
20
6.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
36.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
8
16
8
8
8
0
0
8
0
0
31
% A
% Cys:
8
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
0
0
8
8
0
0
0
0
0
0
8
8
0
0
0
% D
% Glu:
0
0
8
31
24
24
31
0
16
8
31
8
8
8
8
% E
% Phe:
0
0
8
0
0
16
0
8
0
0
8
0
0
0
0
% F
% Gly:
8
0
0
0
0
0
0
8
8
0
8
0
8
8
16
% G
% His:
0
0
8
0
0
0
8
0
0
0
0
0
0
0
8
% H
% Ile:
0
16
0
8
8
0
0
0
0
0
8
0
0
16
0
% I
% Lys:
0
16
8
0
8
0
0
24
16
31
16
8
16
16
8
% K
% Leu:
16
24
8
8
8
0
24
24
0
16
8
16
8
0
8
% L
% Met:
0
0
0
0
8
0
0
0
16
0
8
8
0
0
0
% M
% Asn:
0
0
8
8
8
24
16
0
8
0
0
8
0
0
0
% N
% Pro:
16
0
0
8
0
0
0
8
8
8
8
16
31
0
8
% P
% Gln:
0
8
31
0
0
8
0
0
0
8
0
0
8
8
8
% Q
% Arg:
8
0
0
0
0
8
0
0
24
0
0
8
0
0
0
% R
% Ser:
31
8
8
24
8
0
0
0
0
16
0
0
8
31
8
% S
% Thr:
8
0
0
0
8
8
0
24
0
8
0
16
8
8
0
% T
% Val:
8
24
8
8
16
0
0
0
0
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
16
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _