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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CENPF
All Species:
14.55
Human Site:
T3093
Identified Species:
26.67
UniProt:
P49454
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49454
NP_057427.3
3210
367764
T3093
A
D
I
P
T
G
K
T
S
P
Y
I
L
R
R
Chimpanzee
Pan troglodytes
XP_001171549
3114
357698
T2997
A
D
I
P
T
G
K
T
S
P
Y
I
L
R
R
Rhesus Macaque
Macaca mulatta
XP_001105956
3113
357422
T2996
A
D
I
P
T
G
K
T
S
P
Y
I
L
R
R
Dog
Lupus familis
XP_852813
1449
166096
L1333
V
E
D
D
K
Q
K
L
K
K
K
D
E
E
I
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510329
2965
340022
T2843
A
D
I
P
T
G
K
T
S
P
Y
V
L
R
R
Chicken
Gallus gallus
O42184
1433
161009
Q1317
E
S
A
E
D
K
Q
Q
E
I
D
F
L
N
S
Frog
Xenopus laevis
P85120
2058
236320
L1942
S
R
R
L
S
L
A
L
P
K
E
E
T
T
P
Zebra Danio
Brachydanio rerio
XP_002665261
2708
311087
S2592
D
I
P
V
G
E
M
S
P
F
I
V
R
R
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VJE5
1690
189046
N1574
E
T
S
L
A
K
I
N
F
L
N
S
I
I
A
Honey Bee
Apis mellifera
XP_001120388
2064
240016
K1948
Q
N
L
A
K
L
L
K
P
V
E
L
G
A
F
Nematode Worm
Caenorhab. elegans
P02566
1966
225108
K1850
R
R
F
Q
D
A
N
K
N
L
G
R
A
D
R
Sea Urchin
Strong. purpuratus
XP_796801
3636
416057
V3505
F
N
T
S
S
K
R
V
T
R
S
H
L
S
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P25386
1790
206434
Q1674
K
F
Q
V
E
K
S
Q
L
D
E
K
A
M
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.8
91.4
32.8
N.A.
N.A.
N.A.
N.A.
50.5
20.4
21.5
31.3
N.A.
21.3
22.9
20.1
22
Protein Similarity:
100
96.4
93.8
39.1
N.A.
N.A.
N.A.
N.A.
67.5
32.4
38.6
51.2
N.A.
35.2
41.3
36.4
43.7
P-Site Identity:
100
100
100
6.6
N.A.
N.A.
N.A.
N.A.
93.3
6.6
0
6.6
N.A.
0
0
6.6
6.6
P-Site Similarity:
100
100
100
13.3
N.A.
N.A.
N.A.
N.A.
100
13.3
13.3
20
N.A.
6.6
20
13.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
36.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
31
0
8
8
8
8
8
0
0
0
0
0
16
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
31
8
8
16
0
0
0
0
8
8
8
0
8
0
% D
% Glu:
16
8
0
8
8
8
0
0
8
0
24
8
8
8
0
% E
% Phe:
8
8
8
0
0
0
0
0
8
8
0
8
0
0
8
% F
% Gly:
0
0
0
0
8
31
0
0
0
0
8
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
8
31
0
0
0
8
0
0
8
8
24
8
8
8
% I
% Lys:
8
0
0
0
16
31
39
16
8
16
8
8
0
0
0
% K
% Leu:
0
0
8
16
0
16
8
16
8
16
0
8
47
0
8
% L
% Met:
0
0
0
0
0
0
8
0
0
0
0
0
0
8
0
% M
% Asn:
0
16
0
0
0
0
8
8
8
0
8
0
0
8
8
% N
% Pro:
0
0
8
31
0
0
0
0
24
31
0
0
0
0
8
% P
% Gln:
8
0
8
8
0
8
8
16
0
0
0
0
0
0
0
% Q
% Arg:
8
16
8
0
0
0
8
0
0
8
0
8
8
39
39
% R
% Ser:
8
8
8
8
16
0
8
8
31
0
8
8
0
8
8
% S
% Thr:
0
8
8
0
31
0
0
31
8
0
0
0
8
8
8
% T
% Val:
8
0
0
16
0
0
0
8
0
8
0
16
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
31
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _