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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UBE2A All Species: 36.67
Human Site: S104 Identified Species: 50.42
UniProt: P49459 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P49459 NP_003327.2 152 17315 S104 S P T Y D V S S I L T S I Q S
Chimpanzee Pan troglodytes XP_001137388 247 26879 S199 S P T Y D V S S I L T S I Q S
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_549217 224 24534 S176 S P T Y D V S S I L T S I Q S
Cat Felis silvestris
Mouse Mus musculus Q9Z255 152 17297 S104 S P T Y D V S S I L T S I Q S
Rat Rattus norvegicus P63149 152 17294 S104 S P T Y D V S S I L T S I Q S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512900 156 17521 S108 S P T Y D V S S I L T S I Q S
Chicken Gallus gallus
Frog Xenopus laevis P56616 179 19879 T130 S A L Y D V R T I L L S L Q S
Zebra Danio Brachydanio rerio NP_956013 152 17267 S104 S P T Y D V S S I L T S I Q S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P25153 151 17134 A104 S P T Y D V S A I L T S I Q S
Honey Bee Apis mellifera XP_624240 151 17198 A104 S P T Y D V S A I L T S I Q S
Nematode Worm Caenorhab. elegans P52478 192 21494 A104 S P T Y D V A A I L T S I Q S
Sea Urchin Strong. purpuratus XP_795976 139 15590 T92 Y D V S A I L T S I Q S L L D
Poplar Tree Populus trichocarpa XP_002319717 152 17330 A104 S P I Y D V A A I L T S I Q S
Maize Zea mays NP_001146868 152 17321 A104 S P I Y D V A A I L T S I Q S
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P25865 152 17263 A104 S P I Y D V A A I L T S I Q S
Baker's Yeast Sacchar. cerevisiae P06104 172 19687 S104 T P T Y D V A S I L T S I Q S
Red Bread Mold Neurospora crassa P52493 151 17245 A104 S P T Y D V A A V L T S I Q S
Conservation
Percent
Protein Identity: 100 61.5 N.A. 67.8 N.A. 100 95.3 N.A. 85.9 N.A. 39.1 98.6 N.A. 87.5 87.5 67.7 82.8
Protein Similarity: 100 61.5 N.A. 67.8 N.A. 100 96.7 N.A. 88.4 N.A. 54.7 99.3 N.A. 93.4 93.4 75.5 86.1
P-Site Identity: 100 100 N.A. 100 N.A. 100 100 N.A. 100 N.A. 60 100 N.A. 93.3 93.3 86.6 6.6
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. 100 N.A. 73.3 100 N.A. 100 100 100 33.3
Percent
Protein Identity: 77.6 76.9 N.A. 75.6 61 67.7
Protein Similarity: 92.1 92.1 N.A. 92.1 75 83.5
P-Site Identity: 80 80 N.A. 80 86.6 80
P-Site Similarity: 93.3 93.3 N.A. 93.3 100 100
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 6 0 0 6 0 36 42 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 6 0 0 95 0 0 0 0 0 0 0 0 0 6 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 18 0 0 6 0 0 89 6 0 0 89 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 6 0 0 0 6 0 0 95 6 0 12 6 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 89 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 6 0 0 95 0 % Q
% Arg: 0 0 0 0 0 0 6 0 0 0 0 0 0 0 0 % R
% Ser: 89 0 0 6 0 0 53 48 6 0 0 100 0 0 95 % S
% Thr: 6 0 71 0 0 0 0 12 0 0 89 0 0 0 0 % T
% Val: 0 0 6 0 0 95 0 0 6 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 6 0 0 95 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _