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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UBE2A
All Species:
55.45
Human Site:
Y137
Identified Species:
76.25
UniProt:
P49459
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49459
NP_003327.2
152
17315
Y137
Y
Q
E
N
K
R
E
Y
E
K
R
V
S
A
I
Chimpanzee
Pan troglodytes
XP_001137388
247
26879
Y232
Y
Q
E
N
K
R
E
Y
E
K
R
V
S
A
I
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_549217
224
24534
Y209
Y
Q
E
N
K
R
E
Y
E
K
R
V
S
A
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z255
152
17297
Y137
Y
Q
E
N
K
R
E
Y
E
K
R
V
S
A
I
Rat
Rattus norvegicus
P63149
152
17294
Y137
Y
Q
E
N
K
R
E
Y
E
K
R
V
S
A
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512900
156
17521
Y141
Y
Q
E
N
K
R
E
Y
E
K
R
V
S
A
I
Chicken
Gallus gallus
Frog
Xenopus laevis
P56616
179
19879
K163
W
Q
N
Q
T
A
Y
K
K
H
L
H
E
Q
Y
Zebra Danio
Brachydanio rerio
NP_956013
152
17267
Y137
Y
Q
E
N
K
R
E
Y
E
K
R
V
S
A
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25153
151
17134
Y137
Y
K
E
N
R
R
E
Y
E
K
R
V
K
A
C
Honey Bee
Apis mellifera
XP_624240
151
17198
Y137
Y
K
E
N
R
R
E
Y
E
K
R
V
K
A
C
Nematode Worm
Caenorhab. elegans
P52478
192
21494
Y137
Y
Q
E
N
R
R
E
Y
E
K
R
V
Q
Q
I
Sea Urchin
Strong. purpuratus
XP_795976
139
15590
K125
N
R
R
E
Y
E
K
K
V
S
A
I
V
E
T
Poplar Tree
Populus trichocarpa
XP_002319717
152
17330
Y137
F
S
E
N
K
R
E
Y
N
R
R
V
R
E
I
Maize
Zea mays
NP_001146868
152
17321
Y137
F
S
E
N
K
R
E
Y
N
R
K
V
R
E
I
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P25865
152
17263
Y137
Y
S
E
S
K
R
E
Y
N
R
R
V
R
D
V
Baker's Yeast
Sacchar. cerevisiae
P06104
172
19687
Y137
F
K
D
H
K
S
Q
Y
V
K
R
V
K
E
T
Red Bread Mold
Neurospora crassa
P52493
151
17245
Y137
Y
K
D
N
R
K
E
Y
H
K
R
V
R
E
T
Conservation
Percent
Protein Identity:
100
61.5
N.A.
67.8
N.A.
100
95.3
N.A.
85.9
N.A.
39.1
98.6
N.A.
87.5
87.5
67.7
82.8
Protein Similarity:
100
61.5
N.A.
67.8
N.A.
100
96.7
N.A.
88.4
N.A.
54.7
99.3
N.A.
93.4
93.4
75.5
86.1
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
100
N.A.
6.6
100
N.A.
73.3
73.3
80
0
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
100
N.A.
20
100
N.A.
86.6
86.6
86.6
20
Percent
Protein Identity:
77.6
76.9
N.A.
75.6
61
67.7
Protein Similarity:
92.1
92.1
N.A.
92.1
75
83.5
P-Site Identity:
60
53.3
N.A.
53.3
33.3
46.6
P-Site Similarity:
73.3
73.3
N.A.
73.3
66.6
73.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
6
0
0
0
0
6
0
0
53
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% C
% Asp:
0
0
12
0
0
0
0
0
0
0
0
0
0
6
0
% D
% Glu:
0
0
77
6
0
6
83
0
59
0
0
0
6
30
0
% E
% Phe:
18
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
6
0
0
0
0
6
6
0
6
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
6
0
0
59
% I
% Lys:
0
24
0
0
65
6
6
12
6
71
6
0
18
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
6
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
6
0
6
77
0
0
0
0
18
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
53
0
6
0
0
6
0
0
0
0
0
6
12
0
% Q
% Arg:
0
6
6
0
24
77
0
0
0
18
83
0
24
0
0
% R
% Ser:
0
18
0
6
0
6
0
0
0
6
0
0
42
0
0
% S
% Thr:
0
0
0
0
6
0
0
0
0
0
0
0
0
0
18
% T
% Val:
0
0
0
0
0
0
0
0
12
0
0
89
6
0
6
% V
% Trp:
6
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
71
0
0
0
6
0
6
89
0
0
0
0
0
0
6
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _