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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PCYT1A
All Species:
25.15
Human Site:
Y240
Identified Species:
39.52
UniProt:
P49585
Number Species:
14
Phosphosite Substitution
Charge Score:
0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49585
NP_005008.2
367
41731
Y240
S
F
I
N
E
K
K
Y
H
L
Q
E
R
V
D
Chimpanzee
Pan troglodytes
XP_001143741
320
37092
E211
Q
K
G
S
L
A
K
E
F
K
T
S
L
A
N
Rhesus Macaque
Macaca mulatta
XP_001090055
338
38695
E229
Q
R
G
Y
T
A
K
E
L
N
V
S
F
I
N
Dog
Lupus familis
XP_535776
367
41764
Y240
S
F
I
N
E
K
K
Y
H
L
Q
E
R
V
D
Cat
Felis silvestris
Mouse
Mus musculus
P49586
367
41648
Y240
S
F
I
N
E
K
K
Y
H
L
Q
E
R
V
D
Rat
Rattus norvegicus
P19836
367
41662
Y240
S
F
I
N
E
K
K
Y
H
L
Q
E
R
V
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517894
294
33692
E184
K
R
K
V
K
D
V
E
E
K
S
K
E
F
V
Chicken
Gallus gallus
XP_422725
367
42078
Y240
S
F
I
N
E
K
K
Y
H
L
Q
E
R
V
D
Frog
Xenopus laevis
NP_001089299
367
41920
F240
S
F
I
N
E
K
R
F
N
L
Q
E
R
V
D
Zebra Danio
Brachydanio rerio
NP_001018571
359
41135
Y237
S
F
I
N
E
K
K
Y
H
L
Q
E
H
V
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_647621
526
58183
F369
S
F
L
S
E
K
K
F
R
L
Q
N
K
M
D
Honey Bee
Apis mellifera
XP_395764
403
46370
F277
S
F
L
N
E
K
K
F
R
L
Q
N
K
F
D
Nematode Worm
Caenorhab. elegans
P49583
362
41751
Y244
G
F
L
A
A
S
K
Y
Q
I
Q
N
K
V
D
Sea Urchin
Strong. purpuratus
XP_001180754
425
48260
F256
G
L
F
N
E
T
K
F
K
V
Q
D
S
V
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P13259
424
49388
L267
S
W
L
K
K
N
E
L
E
F
K
K
H
I
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
58.5
60.7
96.4
N.A.
96.1
96.4
N.A.
77.3
89
86.3
76.2
N.A.
36.1
46.4
37.8
45.4
Protein Similarity:
100
69.2
71.6
98
N.A.
97.5
97.2
N.A.
78.1
95
91.2
84.1
N.A.
46
62
52.3
60
P-Site Identity:
100
6.6
6.6
100
N.A.
100
100
N.A.
0
100
80
93.3
N.A.
53.3
60
40
40
P-Site Similarity:
100
20
20
100
N.A.
100
100
N.A.
13.3
100
100
93.3
N.A.
86.6
80
60
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
34.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
50.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
7
14
0
0
0
0
0
0
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
7
0
0
0
0
0
7
0
0
74
% D
% Glu:
0
0
0
0
67
0
7
20
14
0
0
47
7
0
0
% E
% Phe:
0
67
7
0
0
0
0
27
7
7
0
0
7
14
0
% F
% Gly:
14
0
14
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
40
0
0
0
14
0
0
% H
% Ile:
0
0
47
0
0
0
0
0
0
7
0
0
0
14
0
% I
% Lys:
7
7
7
7
14
60
80
0
7
14
7
14
20
0
0
% K
% Leu:
0
7
27
0
7
0
0
7
7
60
0
0
7
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% M
% Asn:
0
0
0
60
0
7
0
0
7
7
0
20
0
0
20
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
14
0
0
0
0
0
0
0
7
0
74
0
0
0
0
% Q
% Arg:
0
14
0
0
0
0
7
0
14
0
0
0
40
0
0
% R
% Ser:
67
0
0
14
0
7
0
0
0
0
7
14
7
0
0
% S
% Thr:
0
0
0
0
7
7
0
0
0
0
7
0
0
0
0
% T
% Val:
0
0
0
7
0
0
7
0
0
7
7
0
0
60
7
% V
% Trp:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
7
0
0
0
47
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _