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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PCYT1A
All Species:
14.85
Human Site:
Y359
Identified Species:
23.33
UniProt:
P49585
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49585
NP_005008.2
367
41731
Y359
S
R
H
K
A
A
A
Y
D
I
S
E
D
E
E
Chimpanzee
Pan troglodytes
XP_001143741
320
37092
R313
W
A
R
C
R
D
F
R
L
D
N
L
H
K
P
Rhesus Macaque
Macaca mulatta
XP_001090055
338
38695
P331
S
A
R
I
K
L
F
P
I
E
V
A
K
C
F
Dog
Lupus familis
XP_535776
367
41764
Y359
S
R
H
K
A
A
A
Y
D
I
S
E
D
E
E
Cat
Felis silvestris
Mouse
Mus musculus
P49586
367
41648
C359
S
R
C
R
A
V
T
C
D
I
S
E
D
E
E
Rat
Rattus norvegicus
P19836
367
41662
C359
S
R
C
K
A
V
T
C
D
I
S
E
D
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517894
294
33692
C286
S
R
H
K
A
A
A
C
D
I
S
E
D
E
E
Chicken
Gallus gallus
XP_422725
367
42078
Y359
R
N
E
S
A
V
T
Y
D
I
S
E
D
E
E
Frog
Xenopus laevis
NP_001089299
367
41920
Y359
S
R
P
T
A
A
T
Y
D
I
S
E
D
E
E
Zebra Danio
Brachydanio rerio
NP_001018571
359
41135
H350
F
S
P
H
S
G
S
H
H
F
S
K
D
D
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_647621
526
58183
G477
G
S
G
S
G
S
S
G
S
L
N
G
K
Q
R
Honey Bee
Apis mellifera
XP_395764
403
46370
S389
S
Q
S
N
Y
Y
L
S
D
D
Y
S
D
D
E
Nematode Worm
Caenorhab. elegans
P49583
362
41751
K349
E
K
K
E
V
V
K
K
R
S
S
R
N
K
A
Sea Urchin
Strong. purpuratus
XP_001180754
425
48260
E379
V
V
R
D
D
D
E
E
E
E
E
E
E
E
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P13259
424
49388
T398
S
D
S
N
T
N
S
T
P
P
S
E
D
D
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
58.5
60.7
96.4
N.A.
96.1
96.4
N.A.
77.3
89
86.3
76.2
N.A.
36.1
46.4
37.8
45.4
Protein Similarity:
100
69.2
71.6
98
N.A.
97.5
97.2
N.A.
78.1
95
91.2
84.1
N.A.
46
62
52.3
60
P-Site Identity:
100
0
6.6
100
N.A.
66.6
73.3
N.A.
93.3
60
80
13.3
N.A.
0
26.6
6.6
13.3
P-Site Similarity:
100
13.3
6.6
100
N.A.
73.3
73.3
N.A.
93.3
60
80
53.3
N.A.
33.3
40
33.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
34.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
50.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
14
0
0
47
27
20
0
0
0
0
7
0
0
7
% A
% Cys:
0
0
14
7
0
0
0
20
0
0
0
0
0
7
0
% C
% Asp:
0
7
0
7
7
14
0
0
54
14
0
0
67
20
20
% D
% Glu:
7
0
7
7
0
0
7
7
7
14
7
60
7
54
54
% E
% Phe:
7
0
0
0
0
0
14
0
0
7
0
0
0
0
7
% F
% Gly:
7
0
7
0
7
7
0
7
0
0
0
7
0
0
0
% G
% His:
0
0
20
7
0
0
0
7
7
0
0
0
7
0
0
% H
% Ile:
0
0
0
7
0
0
0
0
7
47
0
0
0
0
0
% I
% Lys:
0
7
7
27
7
0
7
7
0
0
0
7
14
14
0
% K
% Leu:
0
0
0
0
0
7
7
0
7
7
0
7
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
7
0
14
0
7
0
0
0
0
14
0
7
0
0
% N
% Pro:
0
0
14
0
0
0
0
7
7
7
0
0
0
0
7
% P
% Gln:
0
7
0
0
0
0
0
0
0
0
0
0
0
7
0
% Q
% Arg:
7
40
20
7
7
0
0
7
7
0
0
7
0
0
7
% R
% Ser:
60
14
14
14
7
7
20
7
7
7
67
7
0
0
0
% S
% Thr:
0
0
0
7
7
0
27
7
0
0
0
0
0
0
0
% T
% Val:
7
7
0
0
7
27
0
0
0
0
7
0
0
0
0
% V
% Trp:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
7
7
0
27
0
0
7
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _