KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AARS
All Species:
19.39
Human Site:
S493
Identified Species:
32.82
UniProt:
P49588
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49588
NP_001596.2
968
106810
S493
K
Y
N
Y
H
L
D
S
S
G
S
Y
V
F
E
Chimpanzee
Pan troglodytes
XP_001169474
968
106822
S493
K
Y
N
Y
H
L
D
S
S
G
S
Y
V
F
E
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536788
968
106758
S493
K
Y
N
Y
H
S
D
S
S
G
S
Y
T
F
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGQ7
968
106890
S493
K
Y
N
Y
Q
S
D
S
S
G
S
Y
V
F
E
Rat
Rattus norvegicus
P50475
968
106772
S493
K
Y
N
Y
H
S
D
S
S
G
S
Y
V
F
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506178
968
106458
A493
K
Y
N
Y
R
A
N
A
S
G
S
Y
E
F
E
Chicken
Gallus gallus
NP_001005836
913
101356
D466
G
E
D
L
L
M
L
D
I
Y
A
I
E
E
L
Frog
Xenopus laevis
NP_001121342
968
107500
A493
K
Y
T
Y
T
S
N
A
E
G
V
Y
E
F
D
Zebra Danio
Brachydanio rerio
NP_001037775
991
109646
D518
K
Y
K
Y
T
S
D
D
N
G
N
Y
E
F
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_523511
966
107723
R495
Y
E
A
V
S
D
E
R
D
S
A
Y
N
Y
G
Honey Bee
Apis mellifera
XP_395392
973
109393
I496
Y
K
V
I
S
N
K
I
Y
E
E
Y
E
F
A
Nematode Worm
Caenorhab. elegans
NP_491281
968
106763
S497
Y
T
F
T
G
E
G
S
D
A
V
Y
K
F
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P36428
1003
110471
S537
G
V
S
A
T
D
D
S
F
K
Y
I
W
F
Q
Baker's Yeast
Sacchar. cerevisiae
P40825
958
107259
E492
K
V
P
K
T
N
D
E
F
K
Y
G
S
A
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
N.A.
95.9
N.A.
95.5
95.1
N.A.
92.7
82.8
83.4
79.9
N.A.
60.9
61.8
57.8
N.A.
Protein Similarity:
100
99.7
N.A.
97.8
N.A.
97.9
97.7
N.A.
96.3
89
91.9
89.1
N.A.
74.9
75.8
74.3
N.A.
P-Site Identity:
100
100
N.A.
86.6
N.A.
86.6
93.3
N.A.
66.6
0
40
53.3
N.A.
6.6
13.3
26.6
N.A.
P-Site Similarity:
100
100
N.A.
86.6
N.A.
86.6
93.3
N.A.
80
20
60
66.6
N.A.
26.6
13.3
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
47.8
50.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
63.9
67.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
0
8
0
15
0
8
15
0
0
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
15
58
15
15
0
0
0
0
0
8
% D
% Glu:
0
15
0
0
0
8
8
8
8
8
8
0
36
8
58
% E
% Phe:
0
0
8
0
0
0
0
0
15
0
0
0
0
79
0
% F
% Gly:
15
0
0
0
8
0
8
0
0
58
0
8
0
0
8
% G
% His:
0
0
0
0
29
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
0
8
8
0
0
15
0
0
0
% I
% Lys:
65
8
8
8
0
0
8
0
0
15
0
0
8
0
0
% K
% Leu:
0
0
0
8
8
15
8
0
0
0
0
0
0
0
8
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
43
0
0
15
15
0
8
0
8
0
8
0
8
% N
% Pro:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
8
% Q
% Arg:
0
0
0
0
8
0
0
8
0
0
0
0
0
0
0
% R
% Ser:
0
0
8
0
15
36
0
50
43
8
43
0
8
0
0
% S
% Thr:
0
8
8
8
29
0
0
0
0
0
0
0
8
0
0
% T
% Val:
0
15
8
8
0
0
0
0
0
0
15
0
29
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% W
% Tyr:
22
58
0
58
0
0
0
0
8
8
15
79
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _