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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AARS All Species: 22.42
Human Site: S554 Identified Species: 37.95
UniProt: P49588 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.23
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P49588 NP_001596.2 968 106810 S554 Y L V K V D D S S E D K T E F
Chimpanzee Pan troglodytes XP_001169474 968 106822 S554 Y L V K V D D S S E D K T E F
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_536788 968 106758 N554 Y L V K V E D N S E D K M E F
Cat Felis silvestris
Mouse Mus musculus Q8BGQ7 968 106890 S554 Y L V K V D D S S E D K T E F
Rat Rattus norvegicus P50475 968 106772 S554 Y L V K V D D S S E D K T E F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506178 968 106458 G554 Y L V K D D D G S E D K T E F
Chicken Gallus gallus NP_001005836 913 101356 I527 S T G Q E C G I V L D R T C F
Frog Xenopus laevis NP_001121342 968 107500 S554 Y M V K E E E S S E D K T E F
Zebra Danio Brachydanio rerio NP_001037775 991 109646 S579 Y M L R E N D S A E D R M E F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_523511 966 107723 E556 A L V K V N D E A N E F L V D
Honey Bee Apis mellifera XP_395392 973 109393 E557 F L T K I D D E D S E V H I K
Nematode Worm Caenorhab. elegans NP_491281 968 106763 E558 V L T K V N D E S N E F N V S
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P36428 1003 110471 T598 L I E G S F G T F N V C N V Q
Baker's Yeast Sacchar. cerevisiae P40825 958 107259 A553 K I V I D D A A E F N V E N V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 N.A. 95.9 N.A. 95.5 95.1 N.A. 92.7 82.8 83.4 79.9 N.A. 60.9 61.8 57.8 N.A.
Protein Similarity: 100 99.7 N.A. 97.8 N.A. 97.9 97.7 N.A. 96.3 89 91.9 89.1 N.A. 74.9 75.8 74.3 N.A.
P-Site Identity: 100 100 N.A. 80 N.A. 100 100 N.A. 86.6 20 73.3 46.6 N.A. 33.3 26.6 33.3 N.A.
P-Site Similarity: 100 100 N.A. 93.3 N.A. 100 100 N.A. 86.6 33.3 93.3 86.6 N.A. 53.3 46.6 46.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 47.8 50.5 N.A.
Protein Similarity: N.A. N.A. N.A. 63.9 67.4 N.A.
P-Site Identity: N.A. N.A. N.A. 0 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 0 0 8 8 15 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 8 0 0 0 0 0 8 0 8 0 % C
% Asp: 0 0 0 0 15 50 72 0 8 0 65 0 0 0 8 % D
% Glu: 0 0 8 0 22 15 8 22 8 58 22 0 8 58 0 % E
% Phe: 8 0 0 0 0 8 0 0 8 8 0 15 0 0 65 % F
% Gly: 0 0 8 8 0 0 15 8 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % H
% Ile: 0 15 0 8 8 0 0 8 0 0 0 0 0 8 0 % I
% Lys: 8 0 0 72 0 0 0 0 0 0 0 50 0 0 8 % K
% Leu: 8 65 8 0 0 0 0 0 0 8 0 0 8 0 0 % L
% Met: 0 15 0 0 0 0 0 0 0 0 0 0 15 0 0 % M
% Asn: 0 0 0 0 0 22 0 8 0 22 8 0 15 8 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 8 % Q
% Arg: 0 0 0 8 0 0 0 0 0 0 0 15 0 0 0 % R
% Ser: 8 0 0 0 8 0 0 43 58 8 0 0 0 0 8 % S
% Thr: 0 8 15 0 0 0 0 8 0 0 0 0 50 0 0 % T
% Val: 8 0 65 0 50 0 0 0 8 0 8 15 0 22 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 58 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _