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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AARS All Species: 41.52
Human Site: S731 Identified Species: 70.26
UniProt: P49588 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P49588 NP_001596.2 968 106810 S731 G G T H L R N S S H A G A F V
Chimpanzee Pan troglodytes XP_001169474 968 106822 S731 G G T H L R N S S H A G A F V
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_536788 968 106758 S731 G G T H L Q N S S H A G A F V
Cat Felis silvestris
Mouse Mus musculus Q8BGQ7 968 106890 S731 G G T H L R N S S H A G A F V
Rat Rattus norvegicus P50475 968 106772 S731 G G T H L R N S S H A G A F V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506178 968 106458 S731 G G T H L R N S G H A G A F V
Chicken Gallus gallus NP_001005836 913 101356 A684 K A I Q G L R A V F D E T Y P
Frog Xenopus laevis NP_001121342 968 107500 S731 G G T H L K N S G H A G P F I
Zebra Danio Brachydanio rerio NP_001037775 991 109646 S756 G G T H L Q N S S H A A P F V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_523511 966 107723 S731 G G T H L R R S G H I M D F V
Honey Bee Apis mellifera XP_395392 973 109393 T733 G G T H L H Y T G H I K N F I
Nematode Worm Caenorhab. elegans NP_491281 968 106763 V732 G G T H L Q N V S H I G R I V
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P36428 1003 110471 T773 G G T H I T N T R E A K A F A
Baker's Yeast Sacchar. cerevisiae P40825 958 107259 T727 G G T H V N K T G D I K Y F V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 N.A. 95.9 N.A. 95.5 95.1 N.A. 92.7 82.8 83.4 79.9 N.A. 60.9 61.8 57.8 N.A.
Protein Similarity: 100 99.7 N.A. 97.8 N.A. 97.9 97.7 N.A. 96.3 89 91.9 89.1 N.A. 74.9 75.8 74.3 N.A.
P-Site Identity: 100 100 N.A. 93.3 N.A. 100 100 N.A. 93.3 0 73.3 80 N.A. 66.6 46.6 66.6 N.A.
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. 93.3 13.3 86.6 86.6 N.A. 66.6 60 73.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 47.8 50.5 N.A.
Protein Similarity: N.A. N.A. N.A. 63.9 67.4 N.A.
P-Site Identity: N.A. N.A. N.A. 53.3 40 N.A.
P-Site Similarity: N.A. N.A. N.A. 66.6 53.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 0 0 0 8 0 0 65 8 50 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 8 8 0 8 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 8 0 8 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 8 0 0 0 86 0 % F
% Gly: 93 93 0 0 8 0 0 0 36 0 0 58 0 0 0 % G
% His: 0 0 0 93 0 8 0 0 0 79 0 0 0 0 0 % H
% Ile: 0 0 8 0 8 0 0 0 0 0 29 0 0 8 15 % I
% Lys: 8 0 0 0 0 8 8 0 0 0 0 22 0 0 0 % K
% Leu: 0 0 0 0 79 8 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % M
% Asn: 0 0 0 0 0 8 72 0 0 0 0 0 8 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 15 0 8 % P
% Gln: 0 0 0 8 0 22 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 43 15 0 8 0 0 0 8 0 0 % R
% Ser: 0 0 0 0 0 0 0 65 50 0 0 0 0 0 0 % S
% Thr: 0 0 93 0 0 8 0 22 0 0 0 0 8 0 0 % T
% Val: 0 0 0 0 8 0 0 8 8 0 0 0 0 0 72 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 8 0 0 0 0 0 8 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _