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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AARS All Species: 23.33
Human Site: S775 Identified Species: 39.49
UniProt: P49588 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.38
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P49588 NP_001596.2 968 106810 S775 E S L K K C L S V M E A K V K
Chimpanzee Pan troglodytes XP_001169474 968 106822 S775 E S M K K C L S V M E A K V K
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_536788 968 106758 S775 E S L K N S L S V M E A K V K
Cat Felis silvestris
Mouse Mus musculus Q8BGQ7 968 106890 S775 E T L K K S L S A M E A K V K
Rat Rattus norvegicus P50475 968 106772 S775 E T L K K S L S A M E V K V K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506178 968 106458 S775 E S L K T A L S V L E A K V K
Chicken Gallus gallus NP_001005836 913 101356 L728 E F C G G T H L Q N S G H A G
Frog Xenopus laevis NP_001121342 968 107500 S775 D A I K V S L S D L E K K V K
Zebra Danio Brachydanio rerio NP_001037775 991 109646 D800 D A L K L S L D A L A E K V K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_523511 966 107723 V775 E A F E Q E I V R L K A T I D
Honey Bee Apis mellifera XP_395392 973 109393 D777 S M L Q N Y L D E L Q I T I E
Nematode Worm Caenorhab. elegans NP_491281 968 106763 E776 D R L T A R L E E E S K H A D
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P36428 1003 110471 E817 S L L E R E V E D A S R A E G
Baker's Yeast Sacchar. cerevisiae P40825 958 107259 D771 E Q F A A D L D A A D K L P F
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 N.A. 95.9 N.A. 95.5 95.1 N.A. 92.7 82.8 83.4 79.9 N.A. 60.9 61.8 57.8 N.A.
Protein Similarity: 100 99.7 N.A. 97.8 N.A. 97.9 97.7 N.A. 96.3 89 91.9 89.1 N.A. 74.9 75.8 74.3 N.A.
P-Site Identity: 100 93.3 N.A. 86.6 N.A. 80 73.3 N.A. 80 6.6 46.6 40 N.A. 13.3 13.3 13.3 N.A.
P-Site Similarity: 100 100 N.A. 86.6 N.A. 86.6 80 N.A. 86.6 6.6 73.3 60 N.A. 60 46.6 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 47.8 50.5 N.A.
Protein Similarity: N.A. N.A. N.A. 63.9 67.4 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 22 0 8 15 8 0 0 29 15 8 43 8 15 0 % A
% Cys: 0 0 8 0 0 15 0 0 0 0 0 0 0 0 0 % C
% Asp: 22 0 0 0 0 8 0 22 15 0 8 0 0 0 15 % D
% Glu: 65 0 0 15 0 15 0 15 15 8 50 8 0 8 8 % E
% Phe: 0 8 15 0 0 0 0 0 0 0 0 0 0 0 8 % F
% Gly: 0 0 0 8 8 0 0 0 0 0 0 8 0 0 15 % G
% His: 0 0 0 0 0 0 8 0 0 0 0 0 15 0 0 % H
% Ile: 0 0 8 0 0 0 8 0 0 0 0 8 0 15 0 % I
% Lys: 0 0 0 58 29 0 0 0 0 0 8 22 58 0 58 % K
% Leu: 0 8 65 0 8 0 79 8 0 36 0 0 8 0 0 % L
% Met: 0 8 8 0 0 0 0 0 0 36 0 0 0 0 0 % M
% Asn: 0 0 0 0 15 0 0 0 0 8 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % P
% Gln: 0 8 0 8 8 0 0 0 8 0 8 0 0 0 0 % Q
% Arg: 0 8 0 0 8 8 0 0 8 0 0 8 0 0 0 % R
% Ser: 15 29 0 0 0 36 0 50 0 0 22 0 0 0 0 % S
% Thr: 0 15 0 8 8 8 0 0 0 0 0 0 15 0 0 % T
% Val: 0 0 0 0 8 0 8 8 29 0 0 8 0 58 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _