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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPM1F
All Species:
5.45
Human Site:
S178
Identified Species:
13.33
UniProt:
P49593
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49593
NP_055449.1
454
49831
S178
D
R
H
V
S
L
P
S
F
N
Q
L
F
G
L
Chimpanzee
Pan troglodytes
XP_523813
716
80142
D214
D
K
H
V
C
I
P
D
F
N
M
L
F
N
L
Rhesus Macaque
Macaca mulatta
XP_001089477
455
49874
S179
D
R
H
V
S
L
P
S
F
N
Q
L
F
G
L
Dog
Lupus familis
XP_543574
484
53263
A217
D
R
H
V
C
L
P
A
F
N
Q
L
F
G
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8CGA0
452
49592
A175
D
R
H
V
S
L
P
A
F
N
H
L
F
G
L
Rat
Rattus norvegicus
Q9WVR7
450
49147
A174
D
R
H
V
S
L
P
A
F
N
H
L
F
G
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415067
435
47552
E161
D
R
H
V
I
L
T
E
F
N
Q
L
F
G
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_697776
424
46214
E162
D
R
H
V
I
L
K
E
F
N
Q
L
L
G
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609899
428
48012
R181
D
R
C
V
C
L
D
R
F
G
E
M
Y
E
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RXV3
311
33229
S86
Y
V
K
Q
N
L
F
S
N
L
I
R
H
P
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
31.7
96
77.8
N.A.
78.8
79
N.A.
N.A.
56.8
N.A.
48.9
N.A.
30.6
N.A.
N.A.
N.A.
Protein Similarity:
100
41.7
96.9
82.6
N.A.
86.3
85.6
N.A.
N.A.
71.5
N.A.
63.2
N.A.
44
N.A.
N.A.
N.A.
P-Site Identity:
100
60
100
86.6
N.A.
86.6
86.6
N.A.
N.A.
80
N.A.
73.3
N.A.
40
N.A.
N.A.
N.A.
P-Site Similarity:
100
73.3
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
80
N.A.
73.3
N.A.
60
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.7
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
30
0
0
0
0
0
0
0
% A
% Cys:
0
0
10
0
30
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
90
0
0
0
0
0
10
10
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
20
0
0
10
0
0
10
0
% E
% Phe:
0
0
0
0
0
0
10
0
90
0
0
0
70
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
10
0
0
0
70
0
% G
% His:
0
0
80
0
0
0
0
0
0
0
20
0
10
0
0
% H
% Ile:
0
0
0
0
20
10
0
0
0
0
10
0
0
0
0
% I
% Lys:
0
10
10
0
0
0
10
0
0
0
0
0
0
0
10
% K
% Leu:
0
0
0
0
0
90
0
0
0
10
0
80
10
0
90
% L
% Met:
0
0
0
0
0
0
0
0
0
0
10
10
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
0
10
80
0
0
0
10
0
% N
% Pro:
0
0
0
0
0
0
60
0
0
0
0
0
0
10
0
% P
% Gln:
0
0
0
10
0
0
0
0
0
0
50
0
0
0
0
% Q
% Arg:
0
80
0
0
0
0
0
10
0
0
0
10
0
0
0
% R
% Ser:
0
0
0
0
40
0
0
30
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% T
% Val:
0
10
0
90
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _