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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPM1F
All Species:
26.36
Human Site:
S253
Identified Species:
64.44
UniProt:
P49593
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49593
NP_055449.1
454
49831
S253
A
K
R
E
R
L
Q
S
G
T
T
G
V
C
A
Chimpanzee
Pan troglodytes
XP_523813
716
80142
C289
A
A
R
E
S
L
R
C
G
T
T
G
V
V
T
Rhesus Macaque
Macaca mulatta
XP_001089477
455
49874
S254
A
K
R
E
R
L
Q
S
G
T
T
G
V
C
A
Dog
Lupus familis
XP_543574
484
53263
S292
A
K
R
E
R
L
Q
S
G
T
T
G
V
C
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8CGA0
452
49592
S250
A
K
R
E
R
L
Q
S
G
T
T
G
V
C
A
Rat
Rattus norvegicus
Q9WVR7
450
49147
S249
A
K
R
E
R
L
Q
S
G
T
T
G
V
C
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415067
435
47552
S236
A
K
R
E
R
L
R
S
G
T
T
G
V
S
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_697776
424
46214
S237
A
K
R
E
R
L
R
S
G
S
T
G
V
A
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609899
428
48012
K256
D
E
R
F
T
Q
K
K
I
T
S
G
T
T
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RXV3
311
33229
R161
G
N
A
I
A
V
S
R
D
H
K
P
D
Q
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
31.7
96
77.8
N.A.
78.8
79
N.A.
N.A.
56.8
N.A.
48.9
N.A.
30.6
N.A.
N.A.
N.A.
Protein Similarity:
100
41.7
96.9
82.6
N.A.
86.3
85.6
N.A.
N.A.
71.5
N.A.
63.2
N.A.
44
N.A.
N.A.
N.A.
P-Site Identity:
100
60
100
100
N.A.
100
100
N.A.
N.A.
86.6
N.A.
73.3
N.A.
20
N.A.
N.A.
N.A.
P-Site Similarity:
100
66.6
100
100
N.A.
100
100
N.A.
N.A.
93.3
N.A.
86.6
N.A.
46.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.7
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
80
10
10
0
10
0
0
0
0
0
0
0
0
10
60
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
0
0
0
50
0
% C
% Asp:
10
0
0
0
0
0
0
0
10
0
0
0
10
0
0
% D
% Glu:
0
10
0
80
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
0
0
0
0
0
80
0
0
90
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% H
% Ile:
0
0
0
10
0
0
0
0
10
0
0
0
0
0
0
% I
% Lys:
0
70
0
0
0
0
10
10
0
0
10
0
0
0
0
% K
% Leu:
0
0
0
0
0
80
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% P
% Gln:
0
0
0
0
0
10
50
0
0
0
0
0
0
10
0
% Q
% Arg:
0
0
90
0
70
0
30
10
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
10
0
10
70
0
10
10
0
0
10
20
% S
% Thr:
0
0
0
0
10
0
0
0
0
80
80
0
10
10
10
% T
% Val:
0
0
0
0
0
10
0
0
0
0
0
0
80
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _