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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPM1F
All Species:
7.14
Human Site:
T448
Identified Species:
17.46
UniProt:
P49593
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49593
NP_055449.1
454
49831
T448
S
S
L
P
E
P
E
T
Q
A
P
P
R
S
_
Chimpanzee
Pan troglodytes
XP_523813
716
80142
N686
S
S
L
P
W
R
Q
N
S
W
K
G
Y
S
E
Rhesus Macaque
Macaca mulatta
XP_001089477
455
49874
T449
S
S
L
P
E
P
E
T
Q
A
P
P
R
S
_
Dog
Lupus familis
XP_543574
484
53263
T478
S
G
L
S
Q
P
E
T
S
T
P
Q
S
S
_
Cat
Felis silvestris
Mouse
Mus musculus
Q8CGA0
452
49592
I445
T
G
L
S
E
L
E
I
S
N
T
S
Q
R
S
Rat
Rattus norvegicus
Q9WVR7
450
49147
I444
T
G
L
S
E
L
E
I
N
T
S
Q
R
S
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415067
435
47552
A419
S
L
E
A
G
D
D
A
R
S
S
P
F
N
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_697776
424
46214
G414
D
T
V
C
R
T
E
G
R
G
A
A
C
A
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609899
428
48012
P421
A
V
V
V
L
L
K
P
R
H
Q
I
E
H
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RXV3
311
33229
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
31.7
96
77.8
N.A.
78.8
79
N.A.
N.A.
56.8
N.A.
48.9
N.A.
30.6
N.A.
N.A.
N.A.
Protein Similarity:
100
41.7
96.9
82.6
N.A.
86.3
85.6
N.A.
N.A.
71.5
N.A.
63.2
N.A.
44
N.A.
N.A.
N.A.
P-Site Identity:
100
33.3
100
50
N.A.
20
35.7
N.A.
N.A.
13.3
N.A.
6.6
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
40
100
57.1
N.A.
33.3
42.8
N.A.
N.A.
40
N.A.
33.3
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.7
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
10
0
0
0
10
0
20
10
10
0
10
10
% A
% Cys:
0
0
0
10
0
0
0
0
0
0
0
0
10
0
0
% C
% Asp:
10
0
0
0
0
10
10
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
10
0
40
0
60
0
0
0
0
0
10
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
10
% F
% Gly:
0
30
0
0
10
0
0
10
0
10
0
10
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
10
0
0
0
10
0
% H
% Ile:
0
0
0
0
0
0
0
20
0
0
0
10
0
0
0
% I
% Lys:
0
0
0
0
0
0
10
0
0
0
10
0
0
0
0
% K
% Leu:
0
10
60
0
10
30
0
0
0
0
0
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
10
10
0
0
0
10
0
% N
% Pro:
0
0
0
30
0
30
0
10
0
0
30
30
0
0
0
% P
% Gln:
0
0
0
0
10
0
10
0
20
0
10
20
10
0
0
% Q
% Arg:
0
0
0
0
10
10
0
0
30
0
0
0
30
10
0
% R
% Ser:
50
30
0
30
0
0
0
0
30
10
20
10
10
50
10
% S
% Thr:
20
10
0
0
0
10
0
30
0
20
10
0
0
0
0
% T
% Val:
0
10
20
10
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
10
0
0
0
0
10
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
40
% _