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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DGKG
All Species:
12.42
Human Site:
S154
Identified Species:
22.78
UniProt:
P49619
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49619
NP_001074213.1
791
89096
S154
P
V
P
R
S
S
S
S
E
S
P
V
V
Y
L
Chimpanzee
Pan troglodytes
XP_001152821
791
89168
S154
P
V
P
R
S
S
S
S
E
S
P
M
V
Y
L
Rhesus Macaque
Macaca mulatta
XP_001092912
791
89195
S154
P
V
P
R
S
S
S
S
E
S
P
V
V
Y
L
Dog
Lupus familis
XP_545239
790
88986
S153
P
V
A
P
S
P
G
S
E
S
P
I
V
Y
L
Cat
Felis silvestris
Mouse
Mus musculus
Q91WG7
788
88505
D160
A
P
V
V
Y
L
K
D
V
V
C
Y
L
S
L
Rat
Rattus norvegicus
P49620
788
88503
P154
P
A
S
S
S
D
A
P
I
V
Y
L
K
D
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511802
697
78726
D114
H
E
M
M
E
E
I
D
Y
D
H
D
G
T
V
Chicken
Gallus gallus
XP_422650
933
102351
P260
A
P
Q
H
P
P
A
P
L
A
Q
V
V
Y
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_696120
893
99287
P233
P
S
P
Q
K
G
S
P
S
P
Q
V
V
F
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q01583
1211
132942
P265
R
K
L
S
H
F
D
P
L
T
L
K
V
P
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q03603
812
91362
P158
E
P
R
I
P
L
K
P
L
I
C
T
L
S
L
Sea Urchin
Strong. purpuratus
XP_001197889
1217
132437
V557
G
S
L
A
H
P
D
V
T
N
Q
V
V
Y
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39017
728
79965
F145
K
C
V
S
M
V
G
F
E
H
V
V
H
Q
W
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
96.8
94
N.A.
89.7
88.2
N.A.
51.3
54.9
N.A.
59.2
N.A.
35.5
N.A.
46
38.3
Protein Similarity:
100
99.7
97.8
95.5
N.A.
94.1
93
N.A.
63.5
65.9
N.A.
72.7
N.A.
46.5
N.A.
63.2
48.8
P-Site Identity:
100
93.3
100
66.6
N.A.
6.6
13.3
N.A.
0
26.6
N.A.
40
N.A.
13.3
N.A.
6.6
20
P-Site Similarity:
100
100
100
73.3
N.A.
13.3
33.3
N.A.
6.6
40
N.A.
53.3
N.A.
20
N.A.
13.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
8
8
8
0
0
16
0
0
8
0
0
0
0
0
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
16
0
0
0
0
% C
% Asp:
0
0
0
0
0
8
16
16
0
8
0
8
0
8
0
% D
% Glu:
8
8
0
0
8
8
0
0
39
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
8
0
8
0
0
0
0
0
8
0
% F
% Gly:
8
0
0
0
0
8
16
0
0
0
0
0
8
0
0
% G
% His:
8
0
0
8
16
0
0
0
0
8
8
0
8
0
0
% H
% Ile:
0
0
0
8
0
0
8
0
8
8
0
8
0
0
0
% I
% Lys:
8
8
0
0
8
0
16
0
0
0
0
8
8
0
0
% K
% Leu:
0
0
16
0
0
16
0
0
24
0
8
8
16
0
70
% L
% Met:
0
0
8
8
8
0
0
0
0
0
0
8
0
0
8
% M
% Asn:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% N
% Pro:
47
24
31
8
16
24
0
39
0
8
31
0
0
8
0
% P
% Gln:
0
0
8
8
0
0
0
0
0
0
24
0
0
8
0
% Q
% Arg:
8
0
8
24
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
16
8
24
39
24
31
31
8
31
0
0
0
16
0
% S
% Thr:
0
0
0
0
0
0
0
0
8
8
0
8
0
8
0
% T
% Val:
0
31
16
8
0
8
0
8
8
16
8
47
62
0
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
0
0
0
8
0
0
0
8
0
8
8
0
47
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _