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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DGKG
All Species:
23.64
Human Site:
S683
Identified Species:
43.33
UniProt:
P49619
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49619
NP_001074213.1
791
89096
S683
N
R
A
V
I
R
E
S
R
K
G
V
T
D
P
Chimpanzee
Pan troglodytes
XP_001152821
791
89168
S683
N
R
A
V
I
R
E
S
R
K
G
V
T
D
P
Rhesus Macaque
Macaca mulatta
XP_001092912
791
89195
S683
N
R
A
V
I
R
E
S
R
K
G
V
T
D
P
Dog
Lupus familis
XP_545239
790
88986
S682
S
R
A
V
I
R
E
S
R
R
V
V
T
D
P
Cat
Felis silvestris
Mouse
Mus musculus
Q91WG7
788
88505
S680
N
R
A
V
I
R
E
S
R
K
S
V
T
D
P
Rat
Rattus norvegicus
P49620
788
88503
S680
N
R
A
V
I
R
E
S
R
K
S
V
T
D
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511802
697
78726
D598
R
T
E
K
K
R
S
D
K
R
A
T
V
T
D
Chicken
Gallus gallus
XP_422650
933
102351
H825
K
K
A
P
E
K
P
H
A
A
V
V
T
D
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_696120
893
99287
T785
K
K
V
P
E
R
M
T
G
S
T
V
T
D
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q01583
1211
132942
F1106
L
R
A
G
D
K
E
F
S
A
T
S
F
N
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q03603
812
91362
F685
K
G
R
M
P
G
L
F
P
M
K
N
A
E
K
Sea Urchin
Strong. purpuratus
XP_001197889
1217
132437
L1118
S
K
K
K
Q
R
K
L
E
K
K
L
Q
R
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39017
728
79965
L629
S
I
S
G
T
W
H
L
G
K
L
Q
V
G
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
96.8
94
N.A.
89.7
88.2
N.A.
51.3
54.9
N.A.
59.2
N.A.
35.5
N.A.
46
38.3
Protein Similarity:
100
99.7
97.8
95.5
N.A.
94.1
93
N.A.
63.5
65.9
N.A.
72.7
N.A.
46.5
N.A.
63.2
48.8
P-Site Identity:
100
100
100
80
N.A.
93.3
93.3
N.A.
6.6
26.6
N.A.
26.6
N.A.
20
N.A.
0
13.3
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
20
40
N.A.
40
N.A.
33.3
N.A.
13.3
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
62
0
0
0
0
0
8
16
8
0
8
0
16
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
0
8
0
0
0
0
0
62
8
% D
% Glu:
0
0
8
0
16
0
54
0
8
0
0
0
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
16
0
0
0
0
8
0
0
% F
% Gly:
0
8
0
16
0
8
0
0
16
0
24
0
0
8
0
% G
% His:
0
0
0
0
0
0
8
8
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
47
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
24
24
8
16
8
16
8
0
8
54
16
0
0
0
8
% K
% Leu:
8
0
0
0
0
0
8
16
0
0
8
8
0
0
8
% L
% Met:
0
0
0
8
0
0
8
0
0
8
0
0
0
0
0
% M
% Asn:
39
0
0
0
0
0
0
0
0
0
0
8
0
8
8
% N
% Pro:
0
0
0
16
8
0
8
0
8
0
0
0
0
0
47
% P
% Gln:
0
0
0
0
8
0
0
0
0
0
0
8
8
0
0
% Q
% Arg:
8
54
8
0
0
70
0
0
47
16
0
0
0
8
0
% R
% Ser:
24
0
8
0
0
0
8
47
8
8
16
8
0
0
8
% S
% Thr:
0
8
0
0
8
0
0
8
0
0
16
8
62
8
0
% T
% Val:
0
0
8
47
0
0
0
0
0
0
16
62
16
0
0
% V
% Trp:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _