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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTPA
All Species:
21.82
Human Site:
S251
Identified Species:
48
UniProt:
P49638
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49638
NP_000361.1
278
31750
S251
E
Y
G
G
E
E
F
S
M
E
D
I
C
Q
E
Chimpanzee
Pan troglodytes
XP_528150
278
31756
S251
E
Y
G
G
E
E
F
S
M
E
D
I
C
Q
E
Rhesus Macaque
Macaca mulatta
XP_001092014
278
31987
S251
E
Y
G
G
E
E
F
S
M
E
D
I
C
Q
E
Dog
Lupus familis
XP_535088
275
30889
S248
E
Y
G
G
A
E
F
S
M
E
D
I
C
Q
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8BWP5
278
31996
S251
E
Y
G
G
K
E
F
S
M
E
D
I
C
Q
E
Rat
Rattus norvegicus
P41034
278
31827
S251
E
Y
G
G
N
E
S
S
M
E
D
I
C
Q
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513043
239
27500
M213
Y
G
G
E
D
F
S
M
E
D
L
C
K
E
W
Chicken
Gallus gallus
XP_001234376
271
30966
V242
Q
E
Y
G
G
Q
G
V
S
F
E
E
L
A
K
Frog
Xenopus laevis
Q5M7E1
332
38511
P255
E
F
G
G
T
L
P
P
Y
D
M
G
T
W
A
Zebra Danio
Brachydanio rerio
Q5SPP0
329
38101
P255
E
L
G
G
M
L
P
P
Y
D
M
G
T
W
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P24280
304
34882
E269
V
K
F
G
G
K
S
E
V
D
E
S
K
G
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
97.8
73.3
N.A.
89.2
88.8
N.A.
67.2
71.2
27.1
29.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
98.9
80.2
N.A.
93.8
93.5
N.A.
79.5
83.8
46
46.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
93.3
86.6
N.A.
6.6
6.6
20
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
100
86.6
N.A.
26.6
33.3
33.3
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
0
0
0
0
0
0
0
10
19
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
10
55
0
0
% C
% Asp:
0
0
0
0
10
0
0
0
0
37
55
0
0
0
0
% D
% Glu:
73
10
0
10
28
55
0
10
10
55
19
10
0
10
55
% E
% Phe:
0
10
10
0
0
10
46
0
0
10
0
0
0
0
0
% F
% Gly:
0
10
82
91
19
0
10
0
0
0
0
19
0
10
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
55
0
0
0
% I
% Lys:
0
10
0
0
10
10
0
0
0
0
0
0
19
0
10
% K
% Leu:
0
10
0
0
0
19
0
0
0
0
10
0
10
0
0
% L
% Met:
0
0
0
0
10
0
0
10
55
0
19
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
19
19
0
0
0
0
0
0
0
% P
% Gln:
10
0
0
0
0
10
0
0
0
0
0
0
0
55
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
28
55
10
0
0
10
0
0
0
% S
% Thr:
0
0
0
0
10
0
0
0
0
0
0
0
19
0
0
% T
% Val:
10
0
0
0
0
0
0
10
10
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
19
10
% W
% Tyr:
10
55
10
0
0
0
0
0
19
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _