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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TTPA All Species: 8.95
Human Site: S6 Identified Species: 19.69
UniProt: P49638 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P49638 NP_000361.1 278 31750 S6 _ _ M A E A R S Q P S A G P Q
Chimpanzee Pan troglodytes XP_528150 278 31756 S6 _ _ M A E A R S Q P L A G P Q
Rhesus Macaque Macaca mulatta XP_001092014 278 31987 S6 _ _ M A E A R S Q P W R G P Q
Dog Lupus familis XP_535088 275 30889 G12 A D L S A R G G E D E A A G S
Cat Felis silvestris
Mouse Mus musculus Q8BWP5 278 31996 P6 _ _ M A E M R P G P L V G K Q
Rat Rattus norvegicus P41034 278 31827 P6 _ _ M A E M R P G P V V G K Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513043 239 27500
Chicken Gallus gallus XP_001234376 271 30966 N6 _ _ M A Q R L N E L P D H S A
Frog Xenopus laevis Q5M7E1 332 38511 N9 T H L H A G L N P E T I E K G
Zebra Danio Brachydanio rerio Q5SPP0 329 38101 S9 T H L Q A G L S P E T L E K A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P24280 304 34882 K7 _ M V T Q Q E K E F L E S Y P
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 97.8 73.3 N.A. 89.2 88.8 N.A. 67.2 71.2 27.1 29.4 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.6 98.9 80.2 N.A. 93.8 93.5 N.A. 79.5 83.8 46 46.2 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 92.3 84.6 6.6 N.A. 53.8 53.8 N.A. 0 15.3 0 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 92.3 84.6 26.6 N.A. 53.8 53.8 N.A. 0 38.4 20 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 25.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 42.4 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 21.4 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 55 28 28 0 0 0 0 0 28 10 0 19 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 0 0 0 0 0 0 0 10 0 10 0 0 0 % D
% Glu: 0 0 0 0 46 0 10 0 28 19 10 10 19 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 19 10 10 19 0 0 0 46 10 10 % G
% His: 0 19 0 10 0 0 0 0 0 0 0 0 10 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 10 0 0 0 0 0 37 0 % K
% Leu: 0 0 28 0 0 0 28 0 0 10 28 10 0 0 0 % L
% Met: 0 10 55 0 0 19 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 19 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 19 19 46 10 0 0 28 10 % P
% Gln: 0 0 0 10 19 10 0 0 28 0 0 0 0 0 46 % Q
% Arg: 0 0 0 0 0 19 46 0 0 0 0 10 0 0 0 % R
% Ser: 0 0 0 10 0 0 0 37 0 0 10 0 10 10 10 % S
% Thr: 19 0 0 10 0 0 0 0 0 0 19 0 0 0 0 % T
% Val: 0 0 10 0 0 0 0 0 0 0 10 19 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % Y
% Spaces: 64 55 0 0 0 0 0 0 0 0 0 0 0 0 0 % _