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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EVX1
All Species:
16.97
Human Site:
S178
Identified Species:
31.11
UniProt:
P49640
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49640
NP_001980.1
407
42440
S178
S
Q
G
T
L
A
C
S
A
S
D
Q
M
R
R
Chimpanzee
Pan troglodytes
A2T756
283
30712
S61
L
G
A
L
E
Q
G
S
P
P
D
I
S
P
Y
Rhesus Macaque
Macaca mulatta
XP_001090913
408
42490
S178
S
Q
G
T
L
A
C
S
A
S
D
Q
M
R
R
Dog
Lupus familis
XP_539493
406
42480
S175
S
Q
G
T
L
A
C
S
A
S
D
Q
M
R
R
Cat
Felis silvestris
Mouse
Mus musculus
P23683
416
43180
S178
S
Q
G
T
L
A
C
S
A
S
D
Q
M
R
R
Rat
Rattus norvegicus
P31246
372
40809
Q150
R
T
A
Y
T
N
T
Q
L
L
E
L
E
K
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509846
426
44951
G189
G
G
G
G
G
G
G
G
G
S
Q
G
S
L
A
Chicken
Gallus gallus
Q08727
375
40980
L153
A
Y
T
N
T
Q
L
L
E
L
E
K
E
F
H
Frog
Xenopus laevis
P50476
388
42004
A164
H
G
S
F
S
A
C
A
G
D
Q
M
R
R
Y
Zebra Danio
Brachydanio rerio
O42365
363
39796
T141
R
R
L
R
T
A
Y
T
N
T
Q
L
L
E
L
Tiger Blowfish
Takifugu rubipres
Q6IEI0
415
44026
A168
Q
S
Q
A
G
L
D
A
G
G
A
G
S
R
R
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q93899
247
26800
S25
L
V
E
M
V
A
A
S
R
A
S
S
F
S
P
Sea Urchin
Strong. purpuratus
NP_999816
297
32819
P75
I
I
L
V
S
R
S
P
S
P
P
V
K
G
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
23.8
98.7
93.1
N.A.
92.3
22.8
N.A.
77.2
23.1
70.2
23.5
22.4
N.A.
N.A.
26.2
29.9
Protein Similarity:
100
32.4
99
94
N.A.
93.2
35.6
N.A.
83
35.6
79.1
35.8
34.7
N.A.
N.A.
36.6
38.8
P-Site Identity:
100
13.3
100
100
N.A.
100
0
N.A.
13.3
0
20
6.6
13.3
N.A.
N.A.
13.3
0
P-Site Similarity:
100
13.3
100
100
N.A.
100
13.3
N.A.
13.3
20
26.6
33.3
20
N.A.
N.A.
26.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
16
8
0
54
8
16
31
8
8
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
39
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
8
0
0
8
39
0
0
0
0
% D
% Glu:
0
0
8
0
8
0
0
0
8
0
16
0
16
8
16
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
0
0
8
8
0
% F
% Gly:
8
24
39
8
16
8
16
8
24
8
0
16
0
8
0
% G
% His:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
8
8
0
0
0
0
0
0
0
0
0
8
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
8
8
8
0
% K
% Leu:
16
0
16
8
31
8
8
8
8
16
0
16
8
8
8
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
8
31
0
0
% M
% Asn:
0
0
0
8
0
8
0
0
8
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
8
8
16
8
0
0
8
8
% P
% Gln:
8
31
8
0
0
16
0
8
0
0
24
31
0
0
0
% Q
% Arg:
16
8
0
8
0
8
0
0
8
0
0
0
8
47
39
% R
% Ser:
31
8
8
0
16
0
8
47
8
39
8
8
24
8
0
% S
% Thr:
0
8
8
31
24
0
8
8
0
8
0
0
0
0
0
% T
% Val:
0
8
0
8
8
0
0
0
0
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
8
0
0
8
0
0
0
0
0
0
0
16
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _