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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EVX1 All Species: 15.45
Human Site: T375 Identified Species: 28.33
UniProt: P49640 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P49640 NP_001980.1 407 42440 T375 S D F T C A S T S R S D S F L
Chimpanzee Pan troglodytes A2T756 283 30712 A252 G G A V P P A A P V A A R E G
Rhesus Macaque Macaca mulatta XP_001090913 408 42490 T376 S D F T C A S T S R S D S F L
Dog Lupus familis XP_539493 406 42480 A372 A A S D F T C A S T S R S D S
Cat Felis silvestris
Mouse Mus musculus P23683 416 43180 A375 R A A A A A A A S D F T C A S
Rat Rattus norvegicus P31246 372 40809 P341 D A L S P S L P G S L G S P V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509846 426 44951 T394 S D F T C A S T T R T D S F L
Chicken Gallus gallus Q08727 375 40980 P344 D A V S P S L P G S L D S P V
Frog Xenopus laevis P50476 388 42004 T356 S D F T C S S T S R S D S F L
Zebra Danio Brachydanio rerio O42365 363 39796 S332 D A V S P S L S E S V D S P I
Tiger Blowfish Takifugu rubipres Q6IEI0 415 44026 D369 S A T A A L P D L T L F A T D
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q93899 247 26800 K216 P H S D D S S K S K N T S S D
Sea Urchin Strong. purpuratus NP_999816 297 32819 R266 D A Y S L H L R S R A E L L H
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 23.8 98.7 93.1 N.A. 92.3 22.8 N.A. 77.2 23.1 70.2 23.5 22.4 N.A. N.A. 26.2 29.9
Protein Similarity: 100 32.4 99 94 N.A. 93.2 35.6 N.A. 83 35.6 79.1 35.8 34.7 N.A. N.A. 36.6 38.8
P-Site Identity: 100 0 100 20 N.A. 13.3 6.6 N.A. 86.6 13.3 93.3 13.3 6.6 N.A. N.A. 20 13.3
P-Site Similarity: 100 13.3 100 26.6 N.A. 20 26.6 N.A. 100 33.3 100 40 13.3 N.A. N.A. 40 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 54 16 16 16 31 16 24 0 0 16 8 8 8 0 % A
% Cys: 0 0 0 0 31 0 8 0 0 0 0 0 8 0 0 % C
% Asp: 31 31 0 16 8 0 0 8 0 8 0 47 0 8 16 % D
% Glu: 0 0 0 0 0 0 0 0 8 0 0 8 0 8 0 % E
% Phe: 0 0 31 0 8 0 0 0 0 0 8 8 0 31 0 % F
% Gly: 8 8 0 0 0 0 0 0 16 0 0 8 0 0 8 % G
% His: 0 8 0 0 0 8 0 0 0 0 0 0 0 0 8 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % I
% Lys: 0 0 0 0 0 0 0 8 0 8 0 0 0 0 0 % K
% Leu: 0 0 8 0 8 8 31 0 8 0 24 0 8 8 31 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % N
% Pro: 8 0 0 0 31 8 8 16 8 0 0 0 0 24 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 8 0 0 0 0 0 0 8 0 39 0 8 8 0 0 % R
% Ser: 39 0 16 31 0 39 39 8 54 24 31 0 70 8 16 % S
% Thr: 0 0 8 31 0 8 0 31 8 16 8 16 0 8 0 % T
% Val: 0 0 16 8 0 0 0 0 0 8 8 0 0 0 16 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _