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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MAN2A2 All Species: 13.33
Human Site: S783 Identified Species: 32.59
UniProt: P49641 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.22
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P49641 NP_006113.2 1139 129282 S783 G L T G L L K S I R R V D E E
Chimpanzee Pan troglodytes XP_001169927 1139 129206 S783 G L T G L L K S I R R V D E E
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_545863 1203 135847 S836 G L T G L L K S I R R V D E E
Cat Felis silvestris
Mouse Mus musculus P27046 1150 131571 V779 R S G L M E K V R R K E D S R
Rat Rattus norvegicus P28494 489 56718 K170 N N M V L K L K E D S S R K F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513225 1105 127152 K783 G L S G F M E K M Y T K E D G
Chicken Gallus gallus
Frog Xenopus laevis NP_001085565 1150 131741 S783 G T T G L L K S I K R A G E E
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24451 1108 126703 L762 G L L K S I Q L T Q D S P H V
Honey Bee Apis mellifera XP_624759 1134 130379 F781 T V P I H L E F V K Y G T R A
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784331 658 76246 T339 G T L T D Y F T S L W Q H T N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 N.A. 83.4 N.A. 52 26.9 N.A. 52.1 N.A. 70 N.A. N.A. 38.8 40.2 N.A. 34.1
Protein Similarity: 100 99.4 N.A. 87.8 N.A. 68.6 34 N.A. 68.3 N.A. 83.9 N.A. N.A. 56.7 58.1 N.A. 46
P-Site Identity: 100 100 N.A. 100 N.A. 20 6.6 N.A. 20 N.A. 73.3 N.A. N.A. 13.3 6.6 N.A. 6.6
P-Site Similarity: 100 100 N.A. 100 N.A. 33.3 13.3 N.A. 60 N.A. 80 N.A. N.A. 33.3 33.3 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 10 0 0 0 0 10 10 0 40 10 0 % D
% Glu: 0 0 0 0 0 10 20 0 10 0 0 10 10 40 40 % E
% Phe: 0 0 0 0 10 0 10 10 0 0 0 0 0 0 10 % F
% Gly: 70 0 10 50 0 0 0 0 0 0 0 10 10 0 10 % G
% His: 0 0 0 0 10 0 0 0 0 0 0 0 10 10 0 % H
% Ile: 0 0 0 10 0 10 0 0 40 0 0 0 0 0 0 % I
% Lys: 0 0 0 10 0 10 50 20 0 20 10 10 0 10 0 % K
% Leu: 0 50 20 10 50 50 10 10 0 10 0 0 0 0 0 % L
% Met: 0 0 10 0 10 10 0 0 10 0 0 0 0 0 0 % M
% Asn: 10 10 0 0 0 0 0 0 0 0 0 0 0 0 10 % N
% Pro: 0 0 10 0 0 0 0 0 0 0 0 0 10 0 0 % P
% Gln: 0 0 0 0 0 0 10 0 0 10 0 10 0 0 0 % Q
% Arg: 10 0 0 0 0 0 0 0 10 40 40 0 10 10 10 % R
% Ser: 0 10 10 0 10 0 0 40 10 0 10 20 0 10 0 % S
% Thr: 10 20 40 10 0 0 0 10 10 0 10 0 10 10 0 % T
% Val: 0 10 0 10 0 0 0 10 10 0 0 30 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % W
% Tyr: 0 0 0 0 0 10 0 0 0 10 10 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _