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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRIM1
All Species:
19.7
Human Site:
S123
Identified Species:
48.15
UniProt:
P49642
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49642
NP_000937.1
420
49902
S123
D
D
V
R
R
C
C
S
S
A
D
I
C
P
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_849151
319
37820
N31
A
Q
Y
Y
R
W
L
N
Y
G
G
V
I
K
N
Cat
Felis silvestris
Mouse
Mus musculus
P20664
417
49277
S123
D
D
V
R
R
C
C
S
S
A
D
I
C
S
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080819
420
48972
S125
D
D
V
R
R
C
C
S
S
A
D
I
C
P
K
Zebra Danio
Brachydanio rerio
NP_958856
425
49707
S125
D
D
V
R
R
C
C
S
A
A
D
I
C
S
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24317
438
50203
S141
D
E
V
R
T
C
C
S
G
A
G
V
C
L
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34471
410
48078
K120
D
P
V
R
N
C
C
K
D
A
T
V
C
P
K
Sea Urchin
Strong. purpuratus
XP_791278
429
49651
Q133
D
D
V
R
S
C
C
Q
G
A
D
I
C
S
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001143441
453
51974
S152
D
D
V
R
Y
C
C
S
G
A
D
V
C
R
D
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P10363
409
47672
R121
M
D
D
Y
D
A
F
R
T
C
C
S
G
A
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
70.4
N.A.
90.4
N.A.
N.A.
N.A.
N.A.
70.9
67.2
N.A.
41.3
N.A.
39
57.8
Protein Similarity:
100
N.A.
N.A.
72.8
N.A.
95
N.A.
N.A.
N.A.
N.A.
85
83
N.A.
59.5
N.A.
59.7
74.1
P-Site Identity:
100
N.A.
N.A.
6.6
N.A.
93.3
N.A.
N.A.
N.A.
N.A.
100
86.6
N.A.
60
N.A.
60
73.3
P-Site Similarity:
100
N.A.
N.A.
20
N.A.
93.3
N.A.
N.A.
N.A.
N.A.
100
93.3
N.A.
73.3
N.A.
66.6
73.3
Percent
Protein Identity:
N.A.
40.1
N.A.
N.A.
32.1
N.A.
Protein Similarity:
N.A.
60.2
N.A.
N.A.
55.4
N.A.
P-Site Identity:
N.A.
66.6
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
73.3
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
10
0
0
10
80
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
80
80
0
0
10
10
0
80
0
0
% C
% Asp:
80
70
10
0
10
0
0
0
10
0
60
0
0
0
10
% D
% Glu:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
30
10
20
0
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
50
10
0
0
% I
% Lys:
0
0
0
0
0
0
0
10
0
0
0
0
0
10
70
% K
% Leu:
0
0
0
0
0
0
10
0
0
0
0
0
0
10
0
% L
% Met:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
10
0
0
0
0
0
0
10
% N
% Pro:
0
10
0
0
0
0
0
0
0
0
0
0
0
30
0
% P
% Gln:
0
10
0
0
0
0
0
10
0
0
0
0
0
0
10
% Q
% Arg:
0
0
0
80
50
0
0
10
0
0
0
0
0
10
0
% R
% Ser:
0
0
0
0
10
0
0
60
30
0
0
10
0
30
0
% S
% Thr:
0
0
0
0
10
0
0
0
10
0
10
0
0
0
0
% T
% Val:
0
0
80
0
0
0
0
0
0
0
0
40
0
0
0
% V
% Trp:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
20
10
0
0
0
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _