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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRIM1
All Species:
5.15
Human Site:
S190
Identified Species:
12.59
UniProt:
P49642
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49642
NP_000937.1
420
49902
S190
S
G
I
V
E
Y
L
S
L
V
K
G
G
Q
D
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_849151
319
37820
Q90
V
Y
S
H
R
P
N
Q
H
N
T
V
K
L
G
Cat
Felis silvestris
Mouse
Mus musculus
P20664
417
49277
E187
A
V
R
S
G
I
V
E
Y
L
S
L
V
K
G
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080819
420
48972
E189
A
E
R
S
A
V
A
E
Y
L
S
V
V
K
G
Zebra Danio
Brachydanio rerio
NP_958856
425
49707
S192
S
A
V
A
E
Y
L
S
L
V
K
G
G
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24317
438
50203
N208
Y
A
V
A
E
Y
L
N
I
I
T
Y
A
S
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34471
410
48078
A181
L
N
N
Y
Q
R
S
A
I
A
T
R
L
N
L
Sea Urchin
Strong. purpuratus
XP_791278
429
49651
L199
R
S
A
I
A
E
Y
L
S
I
V
K
G
G
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001143441
453
51974
R219
A
A
I
A
D
Y
F
R
V
Y
K
G
G
E
N
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P10363
409
47672
T180
D
K
R
A
R
A
L
T
D
V
Q
R
R
N
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
70.4
N.A.
90.4
N.A.
N.A.
N.A.
N.A.
70.9
67.2
N.A.
41.3
N.A.
39
57.8
Protein Similarity:
100
N.A.
N.A.
72.8
N.A.
95
N.A.
N.A.
N.A.
N.A.
85
83
N.A.
59.5
N.A.
59.7
74.1
P-Site Identity:
100
N.A.
N.A.
0
N.A.
0
N.A.
N.A.
N.A.
N.A.
0
66.6
N.A.
20
N.A.
0
6.6
P-Site Similarity:
100
N.A.
N.A.
0
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
20
86.6
N.A.
46.6
N.A.
20
26.6
Percent
Protein Identity:
N.A.
40.1
N.A.
N.A.
32.1
N.A.
Protein Similarity:
N.A.
60.2
N.A.
N.A.
55.4
N.A.
P-Site Identity:
N.A.
33.3
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
66.6
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
30
30
10
40
20
10
10
10
0
10
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
10
0
0
0
10
0
0
0
0
0
10
% D
% Glu:
0
10
0
0
30
10
0
20
0
0
0
0
0
20
20
% E
% Phe:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
10
% F
% Gly:
0
10
0
0
10
0
0
0
0
0
0
30
40
10
30
% G
% His:
0
0
0
10
0
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
0
0
20
10
0
10
0
0
20
20
0
0
0
0
0
% I
% Lys:
0
10
0
0
0
0
0
0
0
0
30
10
10
20
0
% K
% Leu:
10
0
0
0
0
0
40
10
20
20
0
10
10
10
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
10
0
0
0
10
10
0
10
0
0
0
20
10
% N
% Pro:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
10
0
0
10
0
0
10
0
0
10
0
% Q
% Arg:
10
0
30
0
20
10
0
10
0
0
0
20
10
0
0
% R
% Ser:
20
10
10
20
0
0
10
20
10
0
20
0
0
10
0
% S
% Thr:
0
0
0
0
0
0
0
10
0
0
30
0
0
0
0
% T
% Val:
10
10
20
10
0
10
10
0
10
30
10
20
20
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
10
0
10
0
40
10
0
20
10
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _