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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRIM1
All Species:
5.15
Human Site:
S239
Identified Species:
12.59
UniProt:
P49642
Number Species:
9
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49642
NP_000937.1
420
49902
S239
D
I
L
E
N
K
E
S
W
D
K
I
L
A
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_849151
319
37820
I139
W
T
L
M
T
M
A
I
R
I
I
D
R
A
L
Cat
Felis silvestris
Mouse
Mus musculus
P20664
417
49277
N236
V
G
Q
D
I
L
E
N
K
E
N
W
D
K
I
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080819
420
48972
N238
V
D
Q
D
I
L
E
N
K
Q
C
W
D
K
V
Zebra Danio
Brachydanio rerio
NP_958856
425
49707
S241
D
I
L
G
N
K
E
S
V
D
K
V
L
A
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24317
438
50203
T257
E
D
Q
N
L
F
G
T
P
K
G
V
T
K
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34471
410
48078
D230
V
F
E
K
M
I
Y
D
Q
G
W
L
D
K
E
Sea Urchin
Strong. purpuratus
XP_791278
429
49651
E248
Q
D
I
L
G
D
K
E
S
W
K
K
V
L
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001143441
453
51974
E268
N
Q
Q
L
F
A
S
E
E
R
C
R
K
I
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P10363
409
47672
L229
P
F
F
V
S
I
M
L
E
E
Q
N
P
W
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
70.4
N.A.
90.4
N.A.
N.A.
N.A.
N.A.
70.9
67.2
N.A.
41.3
N.A.
39
57.8
Protein Similarity:
100
N.A.
N.A.
72.8
N.A.
95
N.A.
N.A.
N.A.
N.A.
85
83
N.A.
59.5
N.A.
59.7
74.1
P-Site Identity:
100
N.A.
N.A.
20
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
6.6
80
N.A.
6.6
N.A.
0
6.6
P-Site Similarity:
100
N.A.
N.A.
20
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
26.6
86.6
N.A.
26.6
N.A.
13.3
26.6
Percent
Protein Identity:
N.A.
40.1
N.A.
N.A.
32.1
N.A.
Protein Similarity:
N.A.
60.2
N.A.
N.A.
55.4
N.A.
P-Site Identity:
N.A.
6.6
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
10
0
0
0
0
0
0
30
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
20
0
0
0
0
% C
% Asp:
20
30
0
20
0
10
0
10
0
20
0
10
30
0
0
% D
% Glu:
10
0
10
10
0
0
40
20
20
20
0
0
0
0
20
% E
% Phe:
0
20
10
0
10
10
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
10
10
0
10
0
0
10
10
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
20
10
0
20
20
0
10
0
10
10
10
0
10
10
% I
% Lys:
0
0
0
10
0
20
10
0
20
10
30
10
10
40
0
% K
% Leu:
0
0
30
20
10
20
0
10
0
0
0
10
20
10
50
% L
% Met:
0
0
0
10
10
10
10
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
10
20
0
0
20
0
0
10
10
0
0
0
% N
% Pro:
10
0
0
0
0
0
0
0
10
0
0
0
10
0
0
% P
% Gln:
10
10
40
0
0
0
0
0
10
10
10
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
10
10
0
10
10
0
0
% R
% Ser:
0
0
0
0
10
0
10
20
10
0
0
0
0
0
0
% S
% Thr:
0
10
0
0
10
0
0
10
0
0
0
0
10
0
0
% T
% Val:
30
0
0
10
0
0
0
0
10
0
0
20
10
0
10
% V
% Trp:
10
0
0
0
0
0
0
0
10
10
10
20
0
10
0
% W
% Tyr:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _