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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRIM1
All Species:
8.48
Human Site:
S405
Identified Species:
20.74
UniProt:
P49642
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49642
NP_000937.1
420
49902
S405
F
L
E
N
L
D
K
S
R
K
G
E
L
L
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_849151
319
37820
I305
Y
C
F
P
R
L
D
I
N
V
S
K
G
I
N
Cat
Felis silvestris
Mouse
Mus musculus
P20664
417
49277
S402
F
L
E
N
L
D
K
S
R
K
G
E
L
L
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080819
420
48972
Q404
Q
F
L
D
K
L
D
Q
S
R
K
G
E
L
L
Zebra Danio
Brachydanio rerio
NP_958856
425
49707
M407
L
D
R
F
L
D
S
M
A
R
S
R
K
G
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24317
438
50203
F423
G
V
V
V
F
E
E
F
L
R
K
L
E
R
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34471
410
48078
P396
Y
K
H
G
A
L
A
P
Y
V
E
N
F
E
K
Sea Urchin
Strong. purpuratus
XP_791278
429
49651
T414
F
V
V
S
L
E
K
T
W
K
G
K
L
L
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001143441
453
51974
L434
L
K
A
C
K
E
E
L
E
S
A
Y
S
A
K
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P10363
409
47672
K395
K
N
E
L
G
S
V
K
R
E
R
E
D
D
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
70.4
N.A.
90.4
N.A.
N.A.
N.A.
N.A.
70.9
67.2
N.A.
41.3
N.A.
39
57.8
Protein Similarity:
100
N.A.
N.A.
72.8
N.A.
95
N.A.
N.A.
N.A.
N.A.
85
83
N.A.
59.5
N.A.
59.7
74.1
P-Site Identity:
100
N.A.
N.A.
0
N.A.
100
N.A.
N.A.
N.A.
N.A.
6.6
13.3
N.A.
0
N.A.
6.6
46.6
P-Site Similarity:
100
N.A.
N.A.
20
N.A.
100
N.A.
N.A.
N.A.
N.A.
20
26.6
N.A.
26.6
N.A.
13.3
86.6
Percent
Protein Identity:
N.A.
40.1
N.A.
N.A.
32.1
N.A.
Protein Similarity:
N.A.
60.2
N.A.
N.A.
55.4
N.A.
P-Site Identity:
N.A.
6.6
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
20
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
10
0
10
0
10
0
10
0
0
10
0
% A
% Cys:
0
10
0
10
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
10
0
30
20
0
0
0
0
0
10
10
10
% D
% Glu:
0
0
30
0
0
30
20
0
10
10
10
30
20
10
20
% E
% Phe:
30
10
10
10
10
0
0
10
0
0
0
0
10
0
0
% F
% Gly:
10
0
0
10
10
0
0
0
0
0
30
10
10
10
0
% G
% His:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
10
0
0
0
0
0
10
0
% I
% Lys:
10
20
0
0
20
0
30
10
0
30
20
20
10
0
40
% K
% Leu:
20
20
10
10
40
30
0
10
10
0
0
10
30
40
10
% L
% Met:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
20
0
0
0
0
10
0
0
10
0
0
10
% N
% Pro:
0
0
0
10
0
0
0
10
0
0
0
0
0
0
0
% P
% Gln:
10
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% Q
% Arg:
0
0
10
0
10
0
0
0
30
30
10
10
0
10
0
% R
% Ser:
0
0
0
10
0
10
10
20
10
10
20
0
10
0
10
% S
% Thr:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% T
% Val:
0
20
20
10
0
0
10
0
0
20
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% W
% Tyr:
20
0
0
0
0
0
0
0
10
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _