Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRIM1 All Species: 8.44
Human Site: S414 Identified Species: 20.63
UniProt: P49642 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.22
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P49642 NP_000937.1 420 49902 S414 K G E L L K K S D L Q K D F _
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_849151 319 37820
Cat Felis silvestris
Mouse Mus musculus P20664 417 49277 S411 K G E L L K K S D L Q K D F _
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001080819 420 48972 K413 R K G E L L N K S D L K K E F
Zebra Danio Brachydanio rerio NP_958856 425 49707 L416 R S R K G E M L K K S D L Q K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24317 438 50203 K432 R K L E R S Q K S A S L Q F _
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34471 410 48078
Sea Urchin Strong. purpuratus XP_791278 429 49651 S423 K G K L L E Q S D Q Q M E F _
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001143441 453 51974 Q443 S A Y S A K L Q Q S K N S L V
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P10363 409 47672
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 70.4 N.A. 90.4 N.A. N.A. N.A. N.A. 70.9 67.2 N.A. 41.3 N.A. 39 57.8
Protein Similarity: 100 N.A. N.A. 72.8 N.A. 95 N.A. N.A. N.A. N.A. 85 83 N.A. 59.5 N.A. 59.7 74.1
P-Site Identity: 100 N.A. N.A. 0 N.A. 100 N.A. N.A. N.A. N.A. 13.3 0 N.A. 7.1 N.A. 0 57.1
P-Site Similarity: 100 N.A. N.A. 0 N.A. 100 N.A. N.A. N.A. N.A. 20 13.3 N.A. 21.4 N.A. 0 85.7
Percent
Protein Identity: N.A. 40.1 N.A. N.A. 32.1 N.A.
Protein Similarity: N.A. 60.2 N.A. N.A. 55.4 N.A.
P-Site Identity: N.A. 6.6 N.A. N.A. 0 N.A.
P-Site Similarity: N.A. 13.3 N.A. N.A. 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 0 10 0 0 0 0 10 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 30 10 0 10 20 0 0 % D
% Glu: 0 0 20 20 0 20 0 0 0 0 0 0 10 10 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 40 10 % F
% Gly: 0 30 10 0 10 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 30 20 10 10 0 30 20 20 10 10 10 30 10 0 10 % K
% Leu: 0 0 10 30 40 10 10 10 0 20 10 10 10 10 0 % L
% Met: 0 0 0 0 0 0 10 0 0 0 0 10 0 0 0 % M
% Asn: 0 0 0 0 0 0 10 0 0 0 0 10 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 20 10 10 10 30 0 10 10 0 % Q
% Arg: 30 0 10 0 10 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 10 10 0 10 0 10 0 30 20 10 20 0 10 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 40 % _