KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRIM1
All Species:
23.94
Human Site:
Y16
Identified Species:
58.52
UniProt:
P49642
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49642
NP_000937.1
420
49902
Y16
L
P
E
L
L
K
L
Y
Y
R
R
L
F
P
Y
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_849151
319
37820
Cat
Felis silvestris
Mouse
Mus musculus
P20664
417
49277
Y16
L
P
E
L
L
K
L
Y
Y
R
R
L
F
P
Y
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080819
420
48972
Y18
L
P
D
V
L
P
L
Y
Y
R
R
L
F
P
F
Zebra Danio
Brachydanio rerio
NP_958856
425
49707
Y18
L
P
D
L
L
P
L
Y
Y
R
R
L
F
P
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24317
438
50203
Y35
L
Q
D
M
L
P
V
Y
Y
R
R
L
F
P
H
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34471
410
48078
N18
D
L
P
I
Y
Y
K
N
F
F
P
V
K
P
F
Sea Urchin
Strong. purpuratus
XP_791278
429
49651
Y26
L
P
E
L
L
P
V
Y
Y
K
R
L
F
P
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001143441
453
51974
P42
V
Y
Y
G
K
L
F
P
Y
G
D
F
F
K
W
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P10363
409
47672
Y18
S
S
S
D
M
E
Y
Y
Y
K
S
L
Y
P
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
70.4
N.A.
90.4
N.A.
N.A.
N.A.
N.A.
70.9
67.2
N.A.
41.3
N.A.
39
57.8
Protein Similarity:
100
N.A.
N.A.
72.8
N.A.
95
N.A.
N.A.
N.A.
N.A.
85
83
N.A.
59.5
N.A.
59.7
74.1
P-Site Identity:
100
N.A.
N.A.
0
N.A.
100
N.A.
N.A.
N.A.
N.A.
73.3
80
N.A.
60
N.A.
6.6
73.3
P-Site Similarity:
100
N.A.
N.A.
0
N.A.
100
N.A.
N.A.
N.A.
N.A.
93.3
93.3
N.A.
86.6
N.A.
33.3
93.3
Percent
Protein Identity:
N.A.
40.1
N.A.
N.A.
32.1
N.A.
Protein Similarity:
N.A.
60.2
N.A.
N.A.
55.4
N.A.
P-Site Identity:
N.A.
13.3
N.A.
N.A.
26.6
N.A.
P-Site Similarity:
N.A.
26.6
N.A.
N.A.
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
30
10
0
0
0
0
0
0
10
0
0
0
0
% D
% Glu:
0
0
30
0
0
10
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
10
0
10
10
0
10
70
0
50
% F
% Gly:
0
0
0
10
0
0
0
0
0
10
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% H
% Ile:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
10
20
10
0
0
20
0
0
10
10
0
% K
% Leu:
60
10
0
40
60
10
40
0
0
0
0
70
0
0
0
% L
% Met:
0
0
0
10
10
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% N
% Pro:
0
50
10
0
0
40
0
10
0
0
10
0
0
80
0
% P
% Gln:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
50
60
0
0
0
0
% R
% Ser:
10
10
10
0
0
0
0
0
0
0
10
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
10
0
0
10
0
0
20
0
0
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% W
% Tyr:
0
10
10
0
10
10
10
70
80
0
0
0
10
0
20
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _