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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRIM2
All Species:
19.09
Human Site:
S147
Identified Species:
30
UniProt:
P49643
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49643
NP_000938.2
509
58806
S147
I
Q
D
F
L
K
D
S
Q
L
Q
F
E
A
I
Chimpanzee
Pan troglodytes
XP_001147112
340
39704
L11
S
G
R
K
W
R
K
L
R
L
A
G
D
Q
R
Rhesus Macaque
Macaca mulatta
XP_001110968
509
58730
S147
I
Q
D
F
L
K
D
S
Q
L
Q
F
E
A
I
Dog
Lupus familis
XP_532185
509
58738
S147
I
R
N
F
L
K
D
S
H
L
Q
F
E
A
I
Cat
Felis silvestris
Mouse
Mus musculus
P33610
505
58390
S147
V
Q
S
F
L
K
D
S
H
L
H
F
E
A
I
Rat
Rattus norvegicus
O89044
507
58584
T147
V
Q
S
F
L
K
D
T
H
L
H
F
E
A
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001012898
508
58704
V147
R
Q
K
F
L
D
H
V
N
L
S
F
E
A
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_999947
508
58723
N152
K
T
E
F
L
H
K
N
N
L
K
Y
E
T
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VPH2
533
61417
N159
V
K
Q
F
L
E
A
N
G
F
E
I
H
P
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O02334
503
58255
S162
E
R
E
Q
V
L
D
S
A
L
A
N
V
N
F
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002303780
453
52160
L124
L
F
R
Y
R
F
R
L
L
S
P
E
A
Q
R
Maize
Zea mays
NP_001130651
458
52153
S129
F
R
L
E
N
P
E
S
Q
R
M
L
M
T
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84WJ2
454
52055
K125
R
H
R
F
R
L
K
K
I
E
E
Q
R
A
I
Baker's Yeast
Sacchar. cerevisiae
P20457
528
62244
P178
F
V
Q
S
L
D
L
P
L
L
Q
F
I
S
N
Red Bread Mold
Neurospora crassa
Q8NIZ4
513
59504
L160
R
A
A
F
I
N
S
L
N
L
D
W
E
T
V
Conservation
Percent
Protein Identity:
100
66.8
97
89.9
N.A.
89.3
88.4
N.A.
N.A.
68.5
N.A.
66.2
N.A.
36.4
N.A.
40.4
N.A.
Protein Similarity:
100
66.8
98
94.8
N.A.
93.9
93.7
N.A.
N.A.
82.5
N.A.
80.1
N.A.
57.9
N.A.
59.9
N.A.
P-Site Identity:
100
6.6
100
80
N.A.
73.3
66.6
N.A.
N.A.
53.3
N.A.
26.6
N.A.
13.3
N.A.
20
N.A.
P-Site Similarity:
100
26.6
100
93.3
N.A.
80
80
N.A.
N.A.
53.3
N.A.
60
N.A.
53.3
N.A.
40
N.A.
Percent
Protein Identity:
37.5
39.2
N.A.
38.7
32.5
35.4
Protein Similarity:
56.5
56.3
N.A.
56.1
52
53
P-Site Identity:
0
13.3
N.A.
20
26.6
20
P-Site Similarity:
13.3
26.6
N.A.
26.6
33.3
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
7
0
0
0
7
0
7
0
14
0
7
47
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
14
0
0
14
40
0
0
0
7
0
7
0
0
% D
% Glu:
7
0
14
7
0
7
7
0
0
7
14
7
54
0
7
% E
% Phe:
14
7
0
67
0
7
0
0
0
7
0
47
0
0
7
% F
% Gly:
0
7
0
0
0
0
0
0
7
0
0
7
0
0
0
% G
% His:
0
7
0
0
0
7
7
0
20
0
14
0
7
0
0
% H
% Ile:
20
0
0
0
7
0
0
0
7
0
0
7
7
0
47
% I
% Lys:
7
7
7
7
0
34
20
7
0
0
7
0
0
0
0
% K
% Leu:
7
0
7
0
60
14
7
20
14
74
0
7
0
0
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
7
0
7
0
0
% M
% Asn:
0
0
7
0
7
7
0
14
20
0
0
7
0
7
7
% N
% Pro:
0
0
0
0
0
7
0
7
0
0
7
0
0
7
0
% P
% Gln:
0
34
14
7
0
0
0
0
20
0
27
7
0
14
0
% Q
% Arg:
20
20
20
0
14
7
7
0
7
7
0
0
7
0
14
% R
% Ser:
7
0
14
7
0
0
7
40
0
7
7
0
0
7
0
% S
% Thr:
0
7
0
0
0
0
0
7
0
0
0
0
0
20
0
% T
% Val:
20
7
0
0
7
0
0
7
0
0
0
0
7
0
14
% V
% Trp:
0
0
0
0
7
0
0
0
0
0
0
7
0
0
0
% W
% Tyr:
0
0
0
7
0
0
0
0
0
0
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _