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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRIM2
All Species:
27.27
Human Site:
S169
Identified Species:
42.86
UniProt:
P49643
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49643
NP_000938.2
509
58806
S169
R
E
Q
E
I
V
A
S
S
P
S
L
S
G
L
Chimpanzee
Pan troglodytes
XP_001147112
340
39704
P33
L
Q
F
Y
L
Q
P
P
S
E
N
I
S
L
I
Rhesus Macaque
Macaca mulatta
XP_001110968
509
58730
S169
R
E
Q
E
I
I
A
S
S
P
N
S
S
G
S
Dog
Lupus familis
XP_532185
509
58738
S169
R
E
Q
E
I
L
A
S
S
P
S
L
C
G
S
Cat
Felis silvestris
Mouse
Mus musculus
P33610
505
58390
S169
R
E
Q
D
I
M
A
S
S
P
S
L
S
G
I
Rat
Rattus norvegicus
O89044
507
58584
S169
R
E
Q
D
I
M
A
S
S
P
S
L
S
G
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001012898
508
58704
S169
L
S
N
E
L
Y
M
S
T
P
G
L
S
M
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_999947
508
58723
S174
L
R
D
K
L
I
N
S
S
Y
G
L
S
G
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VPH2
533
61417
S181
V
K
D
G
L
Y
E
S
T
V
G
Q
S
V
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O02334
503
58255
E184
T
E
K
Q
A
M
I
E
D
L
E
A
A
C
Q
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002303780
453
52160
T146
L
P
Y
K
P
V
T
T
A
E
F
E
G
V
K
Maize
Zea mays
NP_001130651
458
52153
A151
L
P
H
S
E
F
E
A
V
K
D
K
L
S
Q
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84WJ2
454
52055
E147
Y
K
A
V
I
G
A
E
L
E
S
L
K
E
R
Baker's Yeast
Sacchar. cerevisiae
P20457
528
62244
S200
H
Q
L
Y
Q
T
V
S
A
S
L
Q
F
Q
L
Red Bread Mold
Neurospora crassa
Q8NIZ4
513
59504
T182
L
A
A
E
L
A
A
T
A
S
F
G
G
Y
K
Conservation
Percent
Protein Identity:
100
66.8
97
89.9
N.A.
89.3
88.4
N.A.
N.A.
68.5
N.A.
66.2
N.A.
36.4
N.A.
40.4
N.A.
Protein Similarity:
100
66.8
98
94.8
N.A.
93.9
93.7
N.A.
N.A.
82.5
N.A.
80.1
N.A.
57.9
N.A.
59.9
N.A.
P-Site Identity:
100
13.3
73.3
80
N.A.
80
80
N.A.
N.A.
33.3
N.A.
33.3
N.A.
13.3
N.A.
6.6
N.A.
P-Site Similarity:
100
46.6
86.6
86.6
N.A.
100
100
N.A.
N.A.
46.6
N.A.
60
N.A.
33.3
N.A.
33.3
N.A.
Percent
Protein Identity:
37.5
39.2
N.A.
38.7
32.5
35.4
Protein Similarity:
56.5
56.3
N.A.
56.1
52
53
P-Site Identity:
6.6
0
N.A.
26.6
13.3
13.3
P-Site Similarity:
26.6
6.6
N.A.
33.3
26.6
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
14
0
7
7
47
7
20
0
0
7
7
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
7
7
0
% C
% Asp:
0
0
14
14
0
0
0
0
7
0
7
0
0
0
0
% D
% Glu:
0
40
0
34
7
0
14
14
0
20
7
7
0
7
0
% E
% Phe:
0
0
7
0
0
7
0
0
0
0
14
0
7
0
0
% F
% Gly:
0
0
0
7
0
7
0
0
0
0
20
7
14
40
0
% G
% His:
7
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
40
14
7
0
0
0
0
7
0
0
20
% I
% Lys:
0
14
7
14
0
0
0
0
0
7
0
7
7
0
14
% K
% Leu:
40
0
7
0
34
7
0
0
7
7
7
47
7
7
14
% L
% Met:
0
0
0
0
0
20
7
0
0
0
0
0
0
7
0
% M
% Asn:
0
0
7
0
0
0
7
0
0
0
14
0
0
0
0
% N
% Pro:
0
14
0
0
7
0
7
7
0
40
0
0
0
0
0
% P
% Gln:
0
14
34
7
7
7
0
0
0
0
0
14
0
7
14
% Q
% Arg:
34
7
0
0
0
0
0
0
0
0
0
0
0
0
7
% R
% Ser:
0
7
0
7
0
0
0
60
47
14
34
7
54
7
20
% S
% Thr:
7
0
0
0
0
7
7
14
14
0
0
0
0
0
0
% T
% Val:
7
0
0
7
0
14
7
0
7
7
0
0
0
14
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
7
14
0
14
0
0
0
7
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _