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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRIM2
All Species:
25.15
Human Site:
S400
Identified Species:
39.52
UniProt:
P49643
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49643
NP_000938.2
509
58806
S400
L
L
K
Q
K
L
Q
S
Y
K
I
S
P
G
G
Chimpanzee
Pan troglodytes
XP_001147112
340
39704
S236
A
L
A
L
T
A
R
S
L
P
A
V
Q
S
D
Rhesus Macaque
Macaca mulatta
XP_001110968
509
58730
S400
L
L
K
Q
K
L
Q
S
Y
K
I
S
P
G
G
Dog
Lupus familis
XP_532185
509
58738
S402
L
L
K
Q
K
L
Q
S
Y
K
I
S
P
A
G
Cat
Felis silvestris
Mouse
Mus musculus
P33610
505
58390
S400
L
L
K
Q
K
M
Q
S
Y
K
I
P
A
S
G
Rat
Rattus norvegicus
O89044
507
58584
T400
L
L
K
Q
K
M
Q
T
Y
K
I
P
A
S
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001012898
508
58704
S400
L
L
K
Q
K
L
Q
S
Y
K
V
P
P
S
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_999947
508
58723
Q404
E
L
L
K
Q
K
L
Q
S
Y
K
I
A
P
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VPH2
533
61417
S409
S
L
K
T
K
L
S
S
Y
G
L
S
A
S
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O02334
503
58255
A399
I
L
R
N
P
P
S
A
V
D
C
H
G
C
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002303780
453
52160
R349
S
I
R
H
N
Y
G
R
E
G
K
R
T
D
Y
Maize
Zea mays
NP_001130651
458
52153
Y354
K
E
G
K
R
T
D
Y
T
P
Y
S
C
Q
N
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84WJ2
454
52055
K350
H
N
Y
G
K
E
G
K
R
T
D
Y
T
P
Y
Baker's Yeast
Sacchar. cerevisiae
P20457
528
62244
S422
W
D
C
H
T
I
L
S
K
P
R
P
G
R
G
Red Bread Mold
Neurospora crassa
Q8NIZ4
513
59504
P407
K
I
L
T
E
H
P
P
G
P
G
E
A
H
G
Conservation
Percent
Protein Identity:
100
66.8
97
89.9
N.A.
89.3
88.4
N.A.
N.A.
68.5
N.A.
66.2
N.A.
36.4
N.A.
40.4
N.A.
Protein Similarity:
100
66.8
98
94.8
N.A.
93.9
93.7
N.A.
N.A.
82.5
N.A.
80.1
N.A.
57.9
N.A.
59.9
N.A.
P-Site Identity:
100
13.3
100
93.3
N.A.
73.3
66.6
N.A.
N.A.
80
N.A.
13.3
N.A.
46.6
N.A.
6.6
N.A.
P-Site Similarity:
100
20
100
93.3
N.A.
80
80
N.A.
N.A.
86.6
N.A.
26.6
N.A.
53.3
N.A.
26.6
N.A.
Percent
Protein Identity:
37.5
39.2
N.A.
38.7
32.5
35.4
Protein Similarity:
56.5
56.3
N.A.
56.1
52
53
P-Site Identity:
0
6.6
N.A.
6.6
13.3
6.6
P-Site Similarity:
13.3
20
N.A.
6.6
20
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
7
0
0
7
0
7
0
0
7
0
34
7
7
% A
% Cys:
0
0
7
0
0
0
0
0
0
0
7
0
7
7
0
% C
% Asp:
0
7
0
0
0
0
7
0
0
7
7
0
0
7
7
% D
% Glu:
7
7
0
0
7
7
0
0
7
0
0
7
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
7
7
0
0
14
0
7
14
7
0
14
14
60
% G
% His:
7
0
0
14
0
7
0
0
0
0
0
7
0
7
0
% H
% Ile:
7
14
0
0
0
7
0
0
0
0
34
7
0
0
0
% I
% Lys:
14
0
47
14
54
7
0
7
7
40
14
0
0
0
0
% K
% Leu:
40
67
14
7
0
34
14
0
7
0
7
0
0
0
0
% L
% Met:
0
0
0
0
0
14
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
7
0
7
7
0
0
0
0
0
0
0
0
0
7
% N
% Pro:
0
0
0
0
7
7
7
7
0
27
0
27
27
14
7
% P
% Gln:
0
0
0
40
7
0
40
7
0
0
0
0
7
7
0
% Q
% Arg:
0
0
14
0
7
0
7
7
7
0
7
7
0
7
0
% R
% Ser:
14
0
0
0
0
0
14
54
7
0
0
34
0
34
0
% S
% Thr:
0
0
0
14
14
7
0
7
7
7
0
0
14
0
0
% T
% Val:
0
0
0
0
0
0
0
0
7
0
7
7
0
0
0
% V
% Trp:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
0
0
7
0
7
47
7
7
7
0
0
14
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _