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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRIM2
All Species:
7.58
Human Site:
S476
Identified Species:
11.9
UniProt:
P49643
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49643
NP_000938.2
509
58806
S476
E
T
P
Q
P
K
P
S
V
Q
K
T
K
D
A
Chimpanzee
Pan troglodytes
XP_001147112
340
39704
Q308
L
R
H
G
G
R
M
Q
Y
G
L
F
L
K
G
Rhesus Macaque
Macaca mulatta
XP_001110968
509
58730
S476
E
T
P
Q
P
K
P
S
I
Q
K
A
K
D
A
Dog
Lupus familis
XP_532185
509
58738
Q474
S
I
Q
P
E
T
P
Q
P
K
P
S
V
Q
K
Cat
Felis silvestris
Mouse
Mus musculus
P33610
505
58390
Q472
I
S
Q
P
E
T
P
Q
H
K
P
S
T
Q
K
Rat
Rattus norvegicus
O89044
507
58584
Q472
A
S
H
P
E
T
P
Q
H
K
P
S
T
Q
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001012898
508
58704
N476
G
N
S
Q
Q
K
N
N
S
Q
E
S
V
N
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_999947
508
58723
S476
E
V
E
M
S
Q
K
S
Q
E
N
P
P
S
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VPH2
533
61417
R490
D
I
K
G
H
G
D
R
S
M
L
M
G
D
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O02334
503
58255
F471
L
I
T
H
P
N
Q
F
Y
E
E
S
Q
K
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002303780
453
52160
F421
Q
L
A
C
T
L
T
F
E
S
I
H
G
S
S
Maize
Zea mays
NP_001130651
458
52153
S426
F
E
T
T
H
G
V
S
C
D
S
G
I
N
H
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84WJ2
454
52055
V422
C
T
L
T
F
E
A
V
Y
G
T
S
C
D
T
Baker's Yeast
Sacchar. cerevisiae
P20457
528
62244
T495
D
L
E
I
G
E
Q
T
H
I
A
H
P
N
L
Red Bread Mold
Neurospora crassa
Q8NIZ4
513
59504
A480
K
D
E
G
I
M
T
A
A
Q
L
E
T
I
V
Conservation
Percent
Protein Identity:
100
66.8
97
89.9
N.A.
89.3
88.4
N.A.
N.A.
68.5
N.A.
66.2
N.A.
36.4
N.A.
40.4
N.A.
Protein Similarity:
100
66.8
98
94.8
N.A.
93.9
93.7
N.A.
N.A.
82.5
N.A.
80.1
N.A.
57.9
N.A.
59.9
N.A.
P-Site Identity:
100
0
86.6
6.6
N.A.
6.6
6.6
N.A.
N.A.
20
N.A.
20
N.A.
6.6
N.A.
6.6
N.A.
P-Site Similarity:
100
6.6
93.3
20
N.A.
26.6
26.6
N.A.
N.A.
53.3
N.A.
33.3
N.A.
13.3
N.A.
33.3
N.A.
Percent
Protein Identity:
37.5
39.2
N.A.
38.7
32.5
35.4
Protein Similarity:
56.5
56.3
N.A.
56.1
52
53
P-Site Identity:
0
6.6
N.A.
13.3
0
6.6
P-Site Similarity:
13.3
13.3
N.A.
26.6
26.6
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
7
0
0
0
7
7
7
0
7
7
0
0
20
% A
% Cys:
7
0
0
7
0
0
0
0
7
0
0
0
7
0
0
% C
% Asp:
14
7
0
0
0
0
7
0
0
7
0
0
0
27
7
% D
% Glu:
20
7
20
0
20
14
0
0
7
14
14
7
0
0
0
% E
% Phe:
7
0
0
0
7
0
0
14
0
0
0
7
0
0
0
% F
% Gly:
7
0
0
20
14
14
0
0
0
14
0
7
14
0
7
% G
% His:
0
0
14
7
14
0
0
0
20
0
0
14
0
0
7
% H
% Ile:
7
20
0
7
7
0
0
0
7
7
7
0
7
7
7
% I
% Lys:
7
0
7
0
0
20
7
0
0
20
14
0
14
14
20
% K
% Leu:
14
14
7
0
0
7
0
0
0
0
20
0
7
0
7
% L
% Met:
0
0
0
7
0
7
7
0
0
7
0
7
0
0
0
% M
% Asn:
0
7
0
0
0
7
7
7
0
0
7
0
0
20
0
% N
% Pro:
0
0
14
20
20
0
34
0
7
0
20
7
14
0
0
% P
% Gln:
7
0
14
20
7
7
14
27
7
27
0
0
7
20
0
% Q
% Arg:
0
7
0
0
0
7
0
7
0
0
0
0
0
0
0
% R
% Ser:
7
14
7
0
7
0
0
27
14
7
7
40
0
14
14
% S
% Thr:
0
20
14
14
7
20
14
7
0
0
7
7
20
0
7
% T
% Val:
0
7
0
0
0
0
7
7
7
0
0
0
14
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
20
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _