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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRIM2
All Species:
7.58
Human Site:
S485
Identified Species:
11.9
UniProt:
P49643
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49643
NP_000938.2
509
58806
S485
Q
K
T
K
D
A
S
S
A
L
A
S
L
N
S
Chimpanzee
Pan troglodytes
XP_001147112
340
39704
G317
G
L
F
L
K
G
I
G
L
T
L
E
Q
A
L
Rhesus Macaque
Macaca mulatta
XP_001110968
509
58730
S485
Q
K
A
K
D
A
S
S
A
L
A
S
L
N
S
Dog
Lupus familis
XP_532185
509
58738
K483
K
P
S
V
Q
K
T
K
D
A
S
S
A
L
A
Cat
Felis silvestris
Mouse
Mus musculus
P33610
505
58390
R481
K
P
S
T
Q
K
T
R
D
A
A
S
A
L
A
Rat
Rattus norvegicus
O89044
507
58584
K481
K
P
S
T
Q
K
T
K
D
A
T
S
A
L
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001012898
508
58704
S485
Q
E
S
V
N
S
N
S
A
P
T
S
S
N
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_999947
508
58723
R485
E
N
P
P
S
A
S
R
P
S
Q
A
N
P
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VPH2
533
61417
D499
M
L
M
G
D
D
D
D
E
L
W
R
I
A
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O02334
503
58255
A480
E
E
S
Q
K
I
V
A
E
R
I
A
A
K
Q
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002303780
453
52160
D430
S
I
H
G
S
S
Y
D
A
G
I
N
H
P
N
Maize
Zea mays
NP_001130651
458
52153
N435
D
S
G
I
N
H
P
N
Q
Y
F
S
E
S
Q
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84WJ2
454
52055
I431
G
T
S
C
D
T
G
I
N
H
P
N
Q
Y
F
Baker's Yeast
Sacchar. cerevisiae
P20457
528
62244
F504
I
A
H
P
N
L
Y
F
E
R
S
R
Q
L
Q
Red Bread Mold
Neurospora crassa
Q8NIZ4
513
59504
P489
Q
L
E
T
I
V
H
P
N
E
Y
F
K
R
S
Conservation
Percent
Protein Identity:
100
66.8
97
89.9
N.A.
89.3
88.4
N.A.
N.A.
68.5
N.A.
66.2
N.A.
36.4
N.A.
40.4
N.A.
Protein Similarity:
100
66.8
98
94.8
N.A.
93.9
93.7
N.A.
N.A.
82.5
N.A.
80.1
N.A.
57.9
N.A.
59.9
N.A.
P-Site Identity:
100
0
93.3
6.6
N.A.
13.3
6.6
N.A.
N.A.
33.3
N.A.
13.3
N.A.
13.3
N.A.
0
N.A.
P-Site Similarity:
100
0
93.3
40
N.A.
40
33.3
N.A.
N.A.
73.3
N.A.
26.6
N.A.
20
N.A.
40
N.A.
Percent
Protein Identity:
37.5
39.2
N.A.
38.7
32.5
35.4
Protein Similarity:
56.5
56.3
N.A.
56.1
52
53
P-Site Identity:
6.6
6.6
N.A.
6.6
0
13.3
P-Site Similarity:
26.6
26.6
N.A.
20
13.3
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
7
0
0
20
0
7
27
20
20
14
27
14
20
% A
% Cys:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
0
0
27
7
7
14
20
0
0
0
0
0
0
% D
% Glu:
14
14
7
0
0
0
0
0
20
7
0
7
7
0
7
% E
% Phe:
0
0
7
0
0
0
0
7
0
0
7
7
0
0
7
% F
% Gly:
14
0
7
14
0
7
7
7
0
7
0
0
0
0
0
% G
% His:
0
0
14
0
0
7
7
0
0
7
0
0
7
0
0
% H
% Ile:
7
7
0
7
7
7
7
7
0
0
14
0
7
0
0
% I
% Lys:
20
14
0
14
14
20
0
14
0
0
0
0
7
7
7
% K
% Leu:
0
20
0
7
0
7
0
0
7
20
7
0
14
27
7
% L
% Met:
7
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
7
0
0
20
0
7
7
14
0
0
14
7
20
7
% N
% Pro:
0
20
7
14
0
0
7
7
7
7
7
0
0
14
0
% P
% Gln:
27
0
0
7
20
0
0
0
7
0
7
0
20
0
20
% Q
% Arg:
0
0
0
0
0
0
0
14
0
14
0
14
0
7
0
% R
% Ser:
7
7
40
0
14
14
20
20
0
7
14
47
7
7
20
% S
% Thr:
0
7
7
20
0
7
20
0
0
7
14
0
0
0
7
% T
% Val:
0
0
0
14
0
7
7
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
14
0
0
7
7
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _