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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRIM2 All Species: 4.55
Human Site: S509 Identified Species: 7.14
UniProt: P49643 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P49643 NP_000938.2 509 58806 S509 E D Y F S E D S _ _ _ _ _ _ _
Chimpanzee Pan troglodytes XP_001147112 340 39704
Rhesus Macaque Macaca mulatta XP_001110968 509 58730 S509 E D Y F S E D S _ _ _ _ _ _ _
Dog Lupus familis XP_532185 509 58738 F507 M E G L E D Y F S E _ _ _ _ _
Cat Felis silvestris
Mouse Mus musculus P33610 505 58390 F505 L E G L E E Y F _ _ _ _ _ _ _
Rat Rattus norvegicus O89044 507 58584 F505 L E G L E D Y F S K _ _ _ _ _
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001012898 508 58704
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_999947 508 58723
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VPH2 533 61417 N523 K D I S E A F N D D L D L T Q
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O02334 503 58255
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002303780 453 52160
Maize Zea mays NP_001130651 458 52153
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q84WJ2 454 52055
Baker's Yeast Sacchar. cerevisiae P20457 528 62244 H528 K L F N N G N H _ _ _ _ _ _ _
Red Bread Mold Neurospora crassa Q8NIZ4 513 59504 G513 Q G D V K M E G _ _ _ _ _ _ _
Conservation
Percent
Protein Identity: 100 66.8 97 89.9 N.A. 89.3 88.4 N.A. N.A. 68.5 N.A. 66.2 N.A. 36.4 N.A. 40.4 N.A.
Protein Similarity: 100 66.8 98 94.8 N.A. 93.9 93.7 N.A. N.A. 82.5 N.A. 80.1 N.A. 57.9 N.A. 59.9 N.A.
P-Site Identity: 100 0 100 0 N.A. 12.5 0 N.A. N.A. 0 N.A. 0 N.A. 6.6 N.A. 0 N.A.
P-Site Similarity: 100 0 100 20 N.A. 25 20 N.A. N.A. 0 N.A. 0 N.A. 20 N.A. 0 N.A.
Percent
Protein Identity: 37.5 39.2 N.A. 38.7 32.5 35.4
Protein Similarity: 56.5 56.3 N.A. 56.1 52 53
P-Site Identity: 0 0 N.A. 0 0 0
P-Site Similarity: 0 0 N.A. 0 50 25
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 20 7 0 0 14 14 0 7 7 0 7 0 0 0 % D
% Glu: 14 20 0 0 27 20 7 0 0 7 0 0 0 0 0 % E
% Phe: 0 0 7 14 0 0 7 20 0 0 0 0 0 0 0 % F
% Gly: 0 7 20 0 0 7 0 7 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % H
% Ile: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 14 0 0 0 7 0 0 0 0 7 0 0 0 0 0 % K
% Leu: 14 7 0 20 0 0 0 0 0 0 7 0 7 0 0 % L
% Met: 7 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 7 7 0 7 7 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 7 14 0 0 14 14 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % T
% Val: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 14 0 0 0 20 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 34 34 47 47 47 47 47 % _