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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRIM2
All Species:
18.18
Human Site:
T281
Identified Species:
28.57
UniProt:
P49643
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49643
NP_000938.2
509
58806
T281
D
Q
I
D
L
L
S
T
K
S
F
P
P
C
M
Chimpanzee
Pan troglodytes
XP_001147112
340
39704
K139
F
S
I
L
P
K
D
K
I
Q
D
F
L
K
D
Rhesus Macaque
Macaca mulatta
XP_001110968
509
58730
T281
D
Q
I
D
S
L
S
T
K
S
F
P
P
C
M
Dog
Lupus familis
XP_532185
509
58738
T283
D
Q
I
D
S
L
S
T
K
S
F
P
P
C
M
Cat
Felis silvestris
Mouse
Mus musculus
P33610
505
58390
T281
D
Q
I
D
S
L
S
T
K
S
F
P
P
C
M
Rat
Rattus norvegicus
O89044
507
58584
T281
D
Q
I
D
S
L
S
T
K
S
F
P
P
C
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001012898
508
58704
V281
E
H
I
D
A
L
S
V
K
S
F
P
L
C
M
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_999947
508
58723
G286
E
Q
I
D
P
L
S
G
K
S
F
P
L
C
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VPH2
533
61417
T293
S
L
D
Q
L
S
K
T
S
M
P
L
C
M
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O02334
503
58255
K300
V
T
R
H
M
I
D
K
L
S
R
R
S
F
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002303780
453
52160
Y252
V
E
T
L
C
T
S
Y
L
G
P
D
Y
S
Q
Maize
Zea mays
NP_001130651
458
52153
Q257
Y
F
G
P
D
Y
S
Q
P
K
D
A
V
D
I
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84WJ2
454
52055
P253
L
S
T
S
Y
L
G
P
D
Y
S
Q
S
N
E
Baker's Yeast
Sacchar. cerevisiae
P20457
528
62244
Q322
V
D
D
E
I
N
A
Q
S
V
W
S
E
E
I
Red Bread Mold
Neurospora crassa
Q8NIZ4
513
59504
I303
A
D
I
S
A
R
N
I
D
T
L
V
N
N
H
Conservation
Percent
Protein Identity:
100
66.8
97
89.9
N.A.
89.3
88.4
N.A.
N.A.
68.5
N.A.
66.2
N.A.
36.4
N.A.
40.4
N.A.
Protein Similarity:
100
66.8
98
94.8
N.A.
93.9
93.7
N.A.
N.A.
82.5
N.A.
80.1
N.A.
57.9
N.A.
59.9
N.A.
P-Site Identity:
100
6.6
93.3
93.3
N.A.
93.3
93.3
N.A.
N.A.
66.6
N.A.
73.3
N.A.
13.3
N.A.
6.6
N.A.
P-Site Similarity:
100
6.6
93.3
93.3
N.A.
93.3
93.3
N.A.
N.A.
73.3
N.A.
80
N.A.
13.3
N.A.
20
N.A.
Percent
Protein Identity:
37.5
39.2
N.A.
38.7
32.5
35.4
Protein Similarity:
56.5
56.3
N.A.
56.1
52
53
P-Site Identity:
6.6
6.6
N.A.
6.6
0
6.6
P-Site Similarity:
13.3
13.3
N.A.
6.6
33.3
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
14
0
7
0
0
0
0
7
0
0
7
% A
% Cys:
0
0
0
0
7
0
0
0
0
0
0
0
7
47
0
% C
% Asp:
34
14
14
47
7
0
14
0
14
0
14
7
0
7
7
% D
% Glu:
14
7
0
7
0
0
0
0
0
0
0
0
7
7
7
% E
% Phe:
7
7
0
0
0
0
0
0
0
0
47
7
0
7
0
% F
% Gly:
0
0
7
0
0
0
7
7
0
7
0
0
0
0
0
% G
% His:
0
7
0
7
0
0
0
0
0
0
0
0
0
0
7
% H
% Ile:
0
0
60
0
7
7
0
7
7
0
0
0
0
0
14
% I
% Lys:
0
0
0
0
0
7
7
14
47
7
0
0
0
7
0
% K
% Leu:
7
7
0
14
14
54
0
0
14
0
7
7
20
0
0
% L
% Met:
0
0
0
0
7
0
0
0
0
7
0
0
0
7
47
% M
% Asn:
0
0
0
0
0
7
7
0
0
0
0
0
7
14
0
% N
% Pro:
0
0
0
7
14
0
0
7
7
0
14
47
34
0
0
% P
% Gln:
0
40
0
7
0
0
0
14
0
7
0
7
0
0
7
% Q
% Arg:
0
0
7
0
0
7
0
0
0
0
7
7
0
0
7
% R
% Ser:
7
14
0
14
27
7
60
0
14
54
7
7
14
7
0
% S
% Thr:
0
7
14
0
0
7
0
40
0
7
0
0
0
0
0
% T
% Val:
20
0
0
0
0
0
0
7
0
7
0
7
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% W
% Tyr:
7
0
0
0
7
7
0
7
0
7
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _