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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRIM2 All Species: 9.39
Human Site: T480 Identified Species: 14.76
UniProt: P49643 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P49643 NP_000938.2 509 58806 T480 P K P S V Q K T K D A S S A L
Chimpanzee Pan troglodytes XP_001147112 340 39704 F312 G R M Q Y G L F L K G I G L T
Rhesus Macaque Macaca mulatta XP_001110968 509 58730 A480 P K P S I Q K A K D A S S A L
Dog Lupus familis XP_532185 509 58738 S478 E T P Q P K P S V Q K T K D A
Cat Felis silvestris
Mouse Mus musculus P33610 505 58390 S476 E T P Q H K P S T Q K T R D A
Rat Rattus norvegicus O89044 507 58584 S476 E T P Q H K P S T Q K T K D A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001012898 508 58704 S480 Q K N N S Q E S V N S N S A P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_999947 508 58723 P480 S Q K S Q E N P P S A S R P S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VPH2 533 61417 M494 H G D R S M L M G D D D D E L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O02334 503 58255 S475 P N Q F Y E E S Q K I V A E R
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002303780 453 52160 H425 T L T F E S I H G S S Y D A G
Maize Zea mays NP_001130651 458 52153 G430 H G V S C D S G I N H P N Q Y
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q84WJ2 454 52055 S426 F E A V Y G T S C D T G I N H
Baker's Yeast Sacchar. cerevisiae P20457 528 62244 H499 G E Q T H I A H P N L Y F E R
Red Bread Mold Neurospora crassa Q8NIZ4 513 59504 E484 I M T A A Q L E T I V H P N E
Conservation
Percent
Protein Identity: 100 66.8 97 89.9 N.A. 89.3 88.4 N.A. N.A. 68.5 N.A. 66.2 N.A. 36.4 N.A. 40.4 N.A.
Protein Similarity: 100 66.8 98 94.8 N.A. 93.9 93.7 N.A. N.A. 82.5 N.A. 80.1 N.A. 57.9 N.A. 59.9 N.A.
P-Site Identity: 100 0 86.6 6.6 N.A. 6.6 6.6 N.A. N.A. 26.6 N.A. 20 N.A. 13.3 N.A. 6.6 N.A.
P-Site Similarity: 100 6.6 93.3 26.6 N.A. 26.6 26.6 N.A. N.A. 66.6 N.A. 33.3 N.A. 13.3 N.A. 40 N.A.
Percent
Protein Identity: 37.5 39.2 N.A. 38.7 32.5 35.4
Protein Similarity: 56.5 56.3 N.A. 56.1 52 53
P-Site Identity: 6.6 6.6 N.A. 6.6 0 6.6
P-Site Similarity: 13.3 20 N.A. 20 20 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 7 7 0 7 7 0 0 20 0 7 27 20 % A
% Cys: 0 0 0 0 7 0 0 0 7 0 0 0 0 0 0 % C
% Asp: 0 0 7 0 0 7 0 0 0 27 7 7 14 20 0 % D
% Glu: 20 14 0 0 7 14 14 7 0 0 0 0 0 20 7 % E
% Phe: 7 0 0 14 0 0 0 7 0 0 0 0 7 0 0 % F
% Gly: 14 14 0 0 0 14 0 7 14 0 7 7 7 0 7 % G
% His: 14 0 0 0 20 0 0 14 0 0 7 7 0 0 7 % H
% Ile: 7 0 0 0 7 7 7 0 7 7 7 7 7 0 0 % I
% Lys: 0 20 7 0 0 20 14 0 14 14 20 0 14 0 0 % K
% Leu: 0 7 0 0 0 0 20 0 7 0 7 0 0 7 20 % L
% Met: 0 7 7 0 0 7 0 7 0 0 0 0 0 0 0 % M
% Asn: 0 7 7 7 0 0 7 0 0 20 0 7 7 14 0 % N
% Pro: 20 0 34 0 7 0 20 7 14 0 0 7 7 7 7 % P
% Gln: 7 7 14 27 7 27 0 0 7 20 0 0 0 7 0 % Q
% Arg: 0 7 0 7 0 0 0 0 0 0 0 0 14 0 14 % R
% Ser: 7 0 0 27 14 7 7 40 0 14 14 20 20 0 7 % S
% Thr: 7 20 14 7 0 0 7 7 20 0 7 20 0 0 7 % T
% Val: 0 0 7 7 7 0 0 0 14 0 7 7 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 20 0 0 0 0 0 0 14 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _