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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRIM2
All Species:
32.12
Human Site:
Y110
Identified Species:
50.48
UniProt:
P49643
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49643
NP_000938.2
509
58806
Y110
H
F
I
L
R
L
A
Y
C
Q
S
E
E
L
R
Chimpanzee
Pan troglodytes
XP_001147112
340
39704
Rhesus Macaque
Macaca mulatta
XP_001110968
509
58730
Y110
H
F
I
L
R
L
A
Y
C
Q
S
E
E
L
R
Dog
Lupus familis
XP_532185
509
58738
Y110
H
F
I
L
R
L
A
Y
C
Q
S
E
D
L
R
Cat
Felis silvestris
Mouse
Mus musculus
P33610
505
58390
Y110
H
F
I
L
R
L
A
Y
C
Q
S
E
D
L
R
Rat
Rattus norvegicus
O89044
507
58584
Y110
H
F
I
L
R
L
A
Y
C
Q
S
E
D
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001012898
508
58704
Y110
H
F
I
L
R
L
A
Y
C
Q
S
E
E
L
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_999947
508
58723
Y115
H
F
I
L
R
L
A
Y
C
Q
T
E
D
L
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VPH2
533
61417
Y122
H
F
I
L
R
L
A
Y
C
R
S
E
D
L
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O02334
503
58255
F130
H
F
I
L
R
L
A
F
C
R
T
P
E
N
Q
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002303780
453
52160
S92
V
T
N
K
D
I
I
S
H
F
V
L
R
L
V
Maize
Zea mays
NP_001130651
458
52153
R97
I
I
S
H
F
V
L
R
L
V
Y
C
R
T
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84WJ2
454
52055
F93
N
K
D
I
I
S
H
F
V
L
R
L
V
Y
C
Baker's Yeast
Sacchar. cerevisiae
P20457
528
62244
F138
H
F
I
L
R
L
C
F
C
R
S
K
E
L
R
Red Bread Mold
Neurospora crassa
Q8NIZ4
513
59504
F123
H
F
I
L
R
L
A
F
A
S
T
E
D
L
R
Conservation
Percent
Protein Identity:
100
66.8
97
89.9
N.A.
89.3
88.4
N.A.
N.A.
68.5
N.A.
66.2
N.A.
36.4
N.A.
40.4
N.A.
Protein Similarity:
100
66.8
98
94.8
N.A.
93.9
93.7
N.A.
N.A.
82.5
N.A.
80.1
N.A.
57.9
N.A.
59.9
N.A.
P-Site Identity:
100
0
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
100
N.A.
86.6
N.A.
80
N.A.
60
N.A.
P-Site Similarity:
100
0
100
100
N.A.
100
100
N.A.
N.A.
100
N.A.
100
N.A.
93.3
N.A.
86.6
N.A.
Percent
Protein Identity:
37.5
39.2
N.A.
38.7
32.5
35.4
Protein Similarity:
56.5
56.3
N.A.
56.1
52
53
P-Site Identity:
6.6
0
N.A.
0
73.3
66.6
P-Site Similarity:
13.3
6.6
N.A.
20
93.3
86.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
67
0
7
0
0
0
0
0
7
% A
% Cys:
0
0
0
0
0
0
7
0
67
0
0
7
0
0
7
% C
% Asp:
0
0
7
0
7
0
0
0
0
0
0
0
40
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
60
34
0
7
% E
% Phe:
0
74
0
0
7
0
0
27
0
7
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
74
0
0
7
0
0
7
0
7
0
0
0
0
0
0
% H
% Ile:
7
7
74
7
7
7
7
0
0
0
0
0
0
0
0
% I
% Lys:
0
7
0
7
0
0
0
0
0
0
0
7
0
0
0
% K
% Leu:
0
0
0
74
0
74
7
0
7
7
0
14
0
74
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
0
7
0
0
0
0
0
0
0
0
0
0
7
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
47
0
0
0
0
7
% Q
% Arg:
0
0
0
0
74
0
0
7
0
20
7
0
14
0
60
% R
% Ser:
0
0
7
0
0
7
0
7
0
7
54
0
0
0
0
% S
% Thr:
0
7
0
0
0
0
0
0
0
0
20
0
0
7
0
% T
% Val:
7
0
0
0
0
7
0
0
7
7
7
0
7
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
54
0
0
7
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _