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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRIM2
All Species:
25.76
Human Site:
Y262
Identified Species:
40.48
UniProt:
P49643
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49643
NP_000938.2
509
58806
Y262
H
S
Y
T
G
Q
D
Y
S
T
Q
G
N
V
G
Chimpanzee
Pan troglodytes
XP_001147112
340
39704
F120
S
E
E
L
R
R
W
F
I
Q
Q
E
M
D
L
Rhesus Macaque
Macaca mulatta
XP_001110968
509
58730
Y262
H
S
Y
T
G
Q
D
Y
S
T
Q
G
N
V
G
Dog
Lupus familis
XP_532185
509
58738
Y264
H
S
Y
T
G
Q
D
Y
S
I
Q
K
N
A
G
Cat
Felis silvestris
Mouse
Mus musculus
P33610
505
58390
Y262
H
S
Y
T
G
Q
D
Y
S
T
Q
K
N
T
G
Rat
Rattus norvegicus
O89044
507
58584
Y262
H
S
Y
T
G
Q
D
Y
S
T
Q
K
S
T
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001012898
508
58704
Y262
H
S
Y
V
G
P
D
Y
S
V
Q
K
N
T
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_999947
508
58723
Y267
H
A
Y
V
G
Q
D
Y
S
I
Q
K
N
V
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VPH2
533
61417
Y274
N
S
Y
T
G
R
D
Y
T
V
C
R
D
A
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O02334
503
58255
D281
N
N
A
Y
S
G
K
D
Y
N
G
E
Q
P
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002303780
453
52160
I233
N
R
K
W
T
S
T
I
R
E
Q
E
K
D
R
Maize
Zea mays
NP_001130651
458
52153
R238
I
K
E
Q
E
K
D
R
L
T
P
I
V
E
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84WJ2
454
52055
R234
W
T
T
T
I
R
E
R
E
K
D
R
L
T
P
Baker's Yeast
Sacchar. cerevisiae
P20457
528
62244
F303
S
G
Y
T
I
A
D
F
N
Q
Q
K
A
N
Q
Red Bread Mold
Neurospora crassa
Q8NIZ4
513
59504
A284
K
N
F
I
T
P
D
A
S
Y
V
G
T
S
S
Conservation
Percent
Protein Identity:
100
66.8
97
89.9
N.A.
89.3
88.4
N.A.
N.A.
68.5
N.A.
66.2
N.A.
36.4
N.A.
40.4
N.A.
Protein Similarity:
100
66.8
98
94.8
N.A.
93.9
93.7
N.A.
N.A.
82.5
N.A.
80.1
N.A.
57.9
N.A.
59.9
N.A.
P-Site Identity:
100
6.6
100
80
N.A.
86.6
80
N.A.
N.A.
66.6
N.A.
73.3
N.A.
40
N.A.
0
N.A.
P-Site Similarity:
100
20
100
80
N.A.
86.6
86.6
N.A.
N.A.
66.6
N.A.
80
N.A.
66.6
N.A.
13.3
N.A.
Percent
Protein Identity:
37.5
39.2
N.A.
38.7
32.5
35.4
Protein Similarity:
56.5
56.3
N.A.
56.1
52
53
P-Site Identity:
6.6
13.3
N.A.
6.6
26.6
20
P-Site Similarity:
13.3
20
N.A.
26.6
40
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
7
0
0
7
0
7
0
0
0
0
7
14
14
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
74
7
0
0
7
0
7
14
7
% D
% Glu:
0
7
14
0
7
0
7
0
7
7
0
20
0
7
0
% E
% Phe:
0
0
7
0
0
0
0
14
0
0
0
0
0
0
0
% F
% Gly:
0
7
0
0
54
7
0
0
0
0
7
20
0
0
47
% G
% His:
47
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
7
0
0
7
14
0
0
7
7
14
0
7
0
0
0
% I
% Lys:
7
7
7
0
0
7
7
0
0
7
0
40
7
0
0
% K
% Leu:
0
0
0
7
0
0
0
0
7
0
0
0
7
0
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% M
% Asn:
20
14
0
0
0
0
0
0
7
7
0
0
40
7
0
% N
% Pro:
0
0
0
0
0
14
0
0
0
0
7
0
0
7
7
% P
% Gln:
0
0
0
7
0
40
0
0
0
14
67
0
7
0
7
% Q
% Arg:
0
7
0
0
7
20
0
14
7
0
0
14
0
0
7
% R
% Ser:
14
47
0
0
7
7
0
0
54
0
0
0
7
7
7
% S
% Thr:
0
7
7
54
14
0
7
0
7
34
0
0
7
27
0
% T
% Val:
0
0
0
14
0
0
0
0
0
14
7
0
7
20
0
% V
% Trp:
7
0
0
7
0
0
7
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
60
7
0
0
0
54
7
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _