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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRIM2 All Species: 29.7
Human Site: Y29 Identified Species: 46.67
UniProt: P49643 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P49643 NP_000938.2 509 58806 Y29 Y P H C L Q F Y L Q P P S E N
Chimpanzee Pan troglodytes XP_001147112 340 39704
Rhesus Macaque Macaca mulatta XP_001110968 509 58730 Y29 Y P H C L Q F Y L Q P P S E N
Dog Lupus familis XP_532185 509 58738 Y29 Y P H S L Q F Y L E P P S E N
Cat Felis silvestris
Mouse Mus musculus P33610 505 58390 Y29 Y P H S L Q F Y L Q P P T E N
Rat Rattus norvegicus O89044 507 58584 Y29 Y P H S L Q F Y L Q P P T E N
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001012898 508 58704 Y29 Y P H S L Q F Y Q E P P T E S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_999947 508 58723 L36 P P L D N I S L I E F E T F A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VPH2 533 61417 Y31 Y P H N V M L Y H Y P P T E D
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O02334 503 58255 Y44 I P E Y L Q L Y Q T P P G D D
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002303780 453 52160 P13 P Q W K K P P P S A N D V V S
Maize Zea mays NP_001130651 458 52153 G18 A A A A A G G G A G A L P T Y
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q84WJ2 454 52055 D14 Q K R T V S N D V V S T P T L
Baker's Yeast Sacchar. cerevisiae P20457 528 62244 K48 S S S S E E E K K L Y A R L Y
Red Bread Mold Neurospora crassa Q8NIZ4 513 59504 Y41 Y P H R L N F Y S T P P T A D
Conservation
Percent
Protein Identity: 100 66.8 97 89.9 N.A. 89.3 88.4 N.A. N.A. 68.5 N.A. 66.2 N.A. 36.4 N.A. 40.4 N.A.
Protein Similarity: 100 66.8 98 94.8 N.A. 93.9 93.7 N.A. N.A. 82.5 N.A. 80.1 N.A. 57.9 N.A. 59.9 N.A.
P-Site Identity: 100 0 100 86.6 N.A. 86.6 86.6 N.A. N.A. 66.6 N.A. 6.6 N.A. 46.6 N.A. 40 N.A.
P-Site Similarity: 100 0 100 93.3 N.A. 93.3 93.3 N.A. N.A. 86.6 N.A. 26.6 N.A. 66.6 N.A. 53.3 N.A.
Percent
Protein Identity: 37.5 39.2 N.A. 38.7 32.5 35.4
Protein Similarity: 56.5 56.3 N.A. 56.1 52 53
P-Site Identity: 0 0 N.A. 0 0 53.3
P-Site Similarity: 6.6 0 N.A. 13.3 6.6 66.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 7 7 7 7 0 0 0 7 7 7 7 0 7 7 % A
% Cys: 0 0 0 14 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 7 0 0 0 7 0 0 0 7 0 7 20 % D
% Glu: 0 0 7 0 7 7 7 0 0 20 0 7 0 47 0 % E
% Phe: 0 0 0 0 0 0 47 0 0 0 7 0 0 7 0 % F
% Gly: 0 0 0 0 0 7 7 7 0 7 0 0 7 0 0 % G
% His: 0 0 54 0 0 0 0 0 7 0 0 0 0 0 0 % H
% Ile: 7 0 0 0 0 7 0 0 7 0 0 0 0 0 0 % I
% Lys: 0 7 0 7 7 0 0 7 7 0 0 0 0 0 0 % K
% Leu: 0 0 7 0 54 0 14 7 34 7 0 7 0 7 7 % L
% Met: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 7 7 7 7 0 0 0 7 0 0 0 34 % N
% Pro: 14 67 0 0 0 7 7 7 0 0 60 60 14 0 0 % P
% Gln: 7 7 0 0 0 47 0 0 14 27 0 0 0 0 0 % Q
% Arg: 0 0 7 7 0 0 0 0 0 0 0 0 7 0 0 % R
% Ser: 7 7 7 34 0 7 7 0 14 0 7 0 20 0 14 % S
% Thr: 0 0 0 7 0 0 0 0 0 14 0 7 40 14 0 % T
% Val: 0 0 0 0 14 0 0 0 7 7 0 0 7 7 0 % V
% Trp: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 54 0 0 7 0 0 0 60 0 7 7 0 0 0 14 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _