KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRIM2
All Species:
22.73
Human Site:
Y345
Identified Species:
35.71
UniProt:
P49643
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49643
NP_000938.2
509
58806
Y345
P
D
K
F
D
K
G
Y
S
Y
N
I
R
H
S
Chimpanzee
Pan troglodytes
XP_001147112
340
39704
E181
S
G
L
K
L
G
F
E
S
I
Y
K
I
P
F
Rhesus Macaque
Macaca mulatta
XP_001110968
509
58730
Y345
P
D
K
F
D
K
G
Y
S
Y
N
I
R
H
S
Dog
Lupus familis
XP_532185
509
58738
Y347
P
D
K
F
D
K
G
Y
A
Y
N
I
R
H
S
Cat
Felis silvestris
Mouse
Mus musculus
P33610
505
58390
Y345
P
D
K
F
D
K
G
Y
S
Y
N
I
R
H
S
Rat
Rattus norvegicus
O89044
507
58584
Y345
P
D
K
F
D
K
G
Y
S
Y
N
I
R
H
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001012898
508
58704
Y345
A
D
K
F
D
K
G
Y
A
Y
S
I
R
H
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_999947
508
58723
A349
D
A
D
K
F
D
K
A
Y
A
Y
S
I
R
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VPH2
533
61417
S354
D
A
D
K
F
T
R
S
Y
E
Y
N
I
Y
H
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O02334
503
58255
E344
G
I
G
L
S
L
D
E
A
I
A
M
M
R
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002303780
453
52160
H294
F
E
K
L
R
E
D
H
H
L
K
H
G
G
R
Maize
Zea mays
NP_001130651
458
52153
R299
H
H
L
K
H
G
G
R
L
Q
F
G
L
F
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84WJ2
454
52055
K295
L
R
E
D
H
H
L
K
H
G
G
R
M
Q
L
Baker's Yeast
Sacchar. cerevisiae
P20457
528
62244
L367
L
F
L
K
G
I
G
L
S
A
D
E
A
L
K
Red Bread Mold
Neurospora crassa
Q8NIZ4
513
59504
L352
G
L
N
L
E
E
C
L
L
F
W
R
Q
S
F
Conservation
Percent
Protein Identity:
100
66.8
97
89.9
N.A.
89.3
88.4
N.A.
N.A.
68.5
N.A.
66.2
N.A.
36.4
N.A.
40.4
N.A.
Protein Similarity:
100
66.8
98
94.8
N.A.
93.9
93.7
N.A.
N.A.
82.5
N.A.
80.1
N.A.
57.9
N.A.
59.9
N.A.
P-Site Identity:
100
6.6
100
93.3
N.A.
100
100
N.A.
N.A.
73.3
N.A.
0
N.A.
0
N.A.
0
N.A.
P-Site Similarity:
100
6.6
100
100
N.A.
100
100
N.A.
N.A.
93.3
N.A.
0
N.A.
6.6
N.A.
13.3
N.A.
Percent
Protein Identity:
37.5
39.2
N.A.
38.7
32.5
35.4
Protein Similarity:
56.5
56.3
N.A.
56.1
52
53
P-Site Identity:
6.6
6.6
N.A.
0
13.3
0
P-Site Similarity:
26.6
6.6
N.A.
6.6
20
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
14
0
0
0
0
0
7
20
14
7
0
7
0
0
% A
% Cys:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% C
% Asp:
14
40
14
7
40
7
14
0
0
0
7
0
0
0
7
% D
% Glu:
0
7
7
0
7
14
0
14
0
7
0
7
0
0
0
% E
% Phe:
7
7
0
40
14
0
7
0
0
7
7
0
0
7
14
% F
% Gly:
14
7
7
0
7
14
54
0
0
7
7
7
7
7
0
% G
% His:
7
7
0
0
14
7
0
7
14
0
0
7
0
40
14
% H
% Ile:
0
7
0
0
0
7
0
0
0
14
0
40
20
0
0
% I
% Lys:
0
0
47
34
0
40
7
7
0
0
7
7
0
0
7
% K
% Leu:
14
7
20
20
7
7
7
14
14
7
0
0
7
7
14
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
7
14
0
0
% M
% Asn:
0
0
7
0
0
0
0
0
0
0
34
7
0
0
7
% N
% Pro:
34
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
7
0
0
7
7
0
% Q
% Arg:
0
7
0
0
7
0
7
7
0
0
0
14
40
14
7
% R
% Ser:
7
0
0
0
7
0
0
7
40
0
7
7
0
7
34
% S
% Thr:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
40
14
40
20
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _