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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CSNK1E
All Species:
45.45
Human Site:
S191
Identified Species:
76.92
UniProt:
P49674
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49674
NP_001885.1
416
47315
S191
T
H
L
G
I
E
Q
S
R
R
D
D
L
E
S
Chimpanzee
Pan troglodytes
XP_515128
385
44007
I182
G
T
A
R
Y
A
S
I
N
T
H
L
G
I
E
Rhesus Macaque
Macaca mulatta
XP_001113761
317
36681
R115
L
A
D
Q
M
I
S
R
I
E
Y
I
H
S
K
Dog
Lupus familis
XP_850168
416
47320
S191
T
H
L
G
I
E
Q
S
R
R
D
D
L
E
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9JMK2
416
47304
S191
T
H
L
G
I
E
Q
S
R
R
D
D
L
E
S
Rat
Rattus norvegicus
P97633
325
37477
R123
L
A
D
Q
M
I
S
R
I
E
Y
V
H
T
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZLL1
416
47453
S191
T
H
L
G
I
E
Q
S
R
R
D
D
L
E
S
Frog
Xenopus laevis
Q5BP74
415
47421
S191
T
H
L
G
I
E
Q
S
R
R
D
D
L
E
S
Zebra Danio
Brachydanio rerio
Q6P3K7
409
46813
S191
T
H
L
G
I
E
Q
S
R
R
D
D
L
E
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O76324
440
47939
S191
T
H
L
G
I
E
Q
S
R
R
D
D
L
E
S
Honey Bee
Apis mellifera
XP_395574
413
47530
S191
T
H
L
G
I
E
Q
S
R
R
D
D
L
E
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_779963
435
49455
S191
T
H
L
G
I
E
Q
S
R
R
D
D
L
E
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P42158
450
50928
S191
T
H
L
G
I
E
Q
S
R
R
D
D
L
E
S
Baker's Yeast
Sacchar. cerevisiae
P29295
494
57322
S191
T
H
L
G
I
E
Q
S
R
R
D
D
L
E
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.5
72.5
99.2
N.A.
98.8
56.9
N.A.
N.A.
97.3
84.3
84.3
N.A.
62.7
67.5
N.A.
67.5
Protein Similarity:
100
92.5
75
99.2
N.A.
99
65.8
N.A.
N.A.
98.5
88.4
88.6
N.A.
72.9
77.4
N.A.
75.4
P-Site Identity:
100
0
0
100
N.A.
100
0
N.A.
N.A.
100
100
100
N.A.
100
100
N.A.
100
P-Site Similarity:
100
0
6.6
100
N.A.
100
6.6
N.A.
N.A.
100
100
100
N.A.
100
100
N.A.
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
56.6
46.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
70
63.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
100
100
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
100
100
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
8
0
0
8
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
15
0
0
0
0
0
0
0
79
79
0
0
0
% D
% Glu:
0
0
0
0
0
79
0
0
0
15
0
0
0
79
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
79
0
0
0
0
0
0
0
0
8
0
0
% G
% His:
0
79
0
0
0
0
0
0
0
0
8
0
15
0
0
% H
% Ile:
0
0
0
0
79
15
0
8
15
0
0
8
0
8
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
15
% K
% Leu:
15
0
79
0
0
0
0
0
0
0
0
8
79
0
0
% L
% Met:
0
0
0
0
15
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
15
0
0
79
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
8
0
0
0
15
79
79
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
22
79
0
0
0
0
0
8
79
% S
% Thr:
79
8
0
0
0
0
0
0
0
8
0
0
0
8
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
0
0
15
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _