KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CSNK1E
All Species:
31.52
Human Site:
Y268
Identified Species:
53.33
UniProt:
P49674
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49674
NP_001885.1
416
47315
Y268
D
D
K
P
D
Y
S
Y
L
R
Q
L
F
R
N
Chimpanzee
Pan troglodytes
XP_515128
385
44007
R259
L
N
F
C
R
S
L
R
F
D
D
K
P
D
Y
Rhesus Macaque
Macaca mulatta
XP_001113761
317
36681
R192
H
L
G
I
E
Q
S
R
R
D
D
L
E
S
L
Dog
Lupus familis
XP_850168
416
47320
Y268
D
D
K
P
D
Y
S
Y
L
R
Q
L
F
R
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9JMK2
416
47304
Y268
D
D
K
P
D
Y
S
Y
L
R
Q
L
F
R
N
Rat
Rattus norvegicus
P97633
325
37477
R200
H
L
G
I
E
Q
S
R
R
D
D
M
E
S
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZLL1
416
47453
Y268
D
D
K
P
D
Y
S
Y
L
R
Q
L
F
R
N
Frog
Xenopus laevis
Q5BP74
415
47421
Y268
D
D
K
P
D
Y
S
Y
L
R
Q
L
F
R
N
Zebra Danio
Brachydanio rerio
Q6P3K7
409
46813
Y268
D
D
K
P
D
Y
S
Y
L
R
Q
L
F
R
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O76324
440
47939
H268
D
Q
R
P
D
Y
C
H
L
R
K
L
F
R
N
Honey Bee
Apis mellifera
XP_395574
413
47530
Y268
E
E
R
P
D
Y
S
Y
L
R
Q
L
F
R
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_779963
435
49455
F268
D
E
K
P
D
Y
S
F
L
R
Q
L
F
R
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P42158
450
50928
Y268
D
D
K
P
D
Y
A
Y
L
K
R
I
F
R
D
Baker's Yeast
Sacchar. cerevisiae
P29295
494
57322
F268
D
E
K
P
D
Y
L
F
L
A
R
L
F
K
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.5
72.5
99.2
N.A.
98.8
56.9
N.A.
N.A.
97.3
84.3
84.3
N.A.
62.7
67.5
N.A.
67.5
Protein Similarity:
100
92.5
75
99.2
N.A.
99
65.8
N.A.
N.A.
98.5
88.4
88.6
N.A.
72.9
77.4
N.A.
75.4
P-Site Identity:
100
0
13.3
100
N.A.
100
6.6
N.A.
N.A.
100
100
100
N.A.
66.6
73.3
N.A.
86.6
P-Site Similarity:
100
6.6
20
100
N.A.
100
20
N.A.
N.A.
100
100
100
N.A.
86.6
93.3
N.A.
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
56.6
46.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
70
63.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
66.6
53.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
100
86.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
8
0
0
8
0
0
0
0
0
% A
% Cys:
0
0
0
8
0
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
72
50
0
0
79
0
0
0
0
22
22
0
0
8
15
% D
% Glu:
8
22
0
0
15
0
0
0
0
0
0
0
15
0
0
% E
% Phe:
0
0
8
0
0
0
0
15
8
0
0
0
79
0
0
% F
% Gly:
0
0
15
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
15
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
15
0
0
0
0
0
0
0
8
0
0
0
% I
% Lys:
0
0
65
0
0
0
0
0
0
8
8
8
0
8
0
% K
% Leu:
8
15
0
0
0
0
15
0
79
0
0
79
0
0
15
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
58
% N
% Pro:
0
0
0
79
0
0
0
0
0
0
0
0
8
0
0
% P
% Gln:
0
8
0
0
0
15
0
0
0
0
58
0
0
0
0
% Q
% Arg:
0
0
15
0
8
0
0
22
15
65
15
0
0
72
0
% R
% Ser:
0
0
0
0
0
8
72
0
0
0
0
0
0
15
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
79
0
58
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _