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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRLHR All Species: 19.09
Human Site: S217 Identified Species: 35
UniProt: P49683 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P49683 NP_004239.1 370 41107 S217 L C E E F W G S Q E R Q R Q L
Chimpanzee Pan troglodytes XP_521659 370 41056 S217 L C E E F W G S Q E R Q R Q L
Rhesus Macaque Macaca mulatta Q9GK74 381 42711 E211 T E K W P G E E K S I Y G T V
Dog Lupus familis XP_544041 370 41069 S217 L C E E F W G S Q E R Q R Q L
Cat Felis silvestris
Mouse Mus musculus Q6VMN6 370 41232 S217 L C E E F W G S Q E R Q R Q I
Rat Rattus norvegicus Q64121 370 41142 S217 L C E E F W G S Q E R Q R Q I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517159 390 43415 P216 C T E K W P S P S N R D A T I
Chicken Gallus gallus Q9DDN6 385 43491 G215 S E K W P G E G Q L N Y G T I
Frog Xenopus laevis P34992 366 42234 P198 Y V C L E D F P E D K F R L S
Zebra Danio Brachydanio rerio NP_001034615 370 41772 G215 I C E E F W M G Q E K E R L A
Tiger Blowfish Takifugu rubipres NP_001098075 411 46956 P240 E A C L E H W P S P Q H R L I
Fruit Fly Dros. melanogaster P25931 464 53506 P266 Y I C R E M W P S R T Q E Y Y
Honey Bee Apis mellifera XP_001123033 393 45480 T199 R K I F S S I T S I L Q F V L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 32.8 94.8 N.A. 90.2 89.4 N.A. 34 32.7 29.7 50.5 31.8 25.8 35.3 N.A. N.A.
Protein Similarity: 100 99.4 55.3 96.4 N.A. 92.9 92.1 N.A. 52.8 54 51.8 64.3 49.6 44.1 54.9 N.A. N.A.
P-Site Identity: 100 100 0 100 N.A. 93.3 93.3 N.A. 13.3 6.6 6.6 53.3 6.6 6.6 13.3 N.A. N.A.
P-Site Similarity: 100 100 20 100 N.A. 100 100 N.A. 33.3 20 26.6 73.3 20 6.6 20 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 0 0 0 0 0 0 0 0 8 0 8 % A
% Cys: 8 47 24 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 8 0 0 0 8 0 8 0 0 0 % D
% Glu: 8 16 54 47 24 0 16 8 8 47 0 8 8 0 0 % E
% Phe: 0 0 0 8 47 0 8 0 0 0 0 8 8 0 0 % F
% Gly: 0 0 0 0 0 16 39 16 0 0 0 0 16 0 0 % G
% His: 0 0 0 0 0 8 0 0 0 0 0 8 0 0 0 % H
% Ile: 8 8 8 0 0 0 8 0 0 8 8 0 0 0 39 % I
% Lys: 0 8 16 8 0 0 0 0 8 0 16 0 0 0 0 % K
% Leu: 39 0 0 16 0 0 0 0 0 8 8 0 0 24 31 % L
% Met: 0 0 0 0 0 8 8 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 8 8 0 0 0 0 % N
% Pro: 0 0 0 0 16 8 0 31 0 8 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 54 0 8 54 0 39 0 % Q
% Arg: 8 0 0 8 0 0 0 0 0 8 47 0 62 0 0 % R
% Ser: 8 0 0 0 8 8 8 39 31 8 0 0 0 0 8 % S
% Thr: 8 8 0 0 0 0 0 8 0 0 8 0 0 24 0 % T
% Val: 0 8 0 0 0 0 0 0 0 0 0 0 0 8 8 % V
% Trp: 0 0 0 16 8 47 16 0 0 0 0 0 0 0 0 % W
% Tyr: 16 0 0 0 0 0 0 0 0 0 0 16 0 8 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _