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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRLHR
All Species:
19.09
Human Site:
S217
Identified Species:
35
UniProt:
P49683
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49683
NP_004239.1
370
41107
S217
L
C
E
E
F
W
G
S
Q
E
R
Q
R
Q
L
Chimpanzee
Pan troglodytes
XP_521659
370
41056
S217
L
C
E
E
F
W
G
S
Q
E
R
Q
R
Q
L
Rhesus Macaque
Macaca mulatta
Q9GK74
381
42711
E211
T
E
K
W
P
G
E
E
K
S
I
Y
G
T
V
Dog
Lupus familis
XP_544041
370
41069
S217
L
C
E
E
F
W
G
S
Q
E
R
Q
R
Q
L
Cat
Felis silvestris
Mouse
Mus musculus
Q6VMN6
370
41232
S217
L
C
E
E
F
W
G
S
Q
E
R
Q
R
Q
I
Rat
Rattus norvegicus
Q64121
370
41142
S217
L
C
E
E
F
W
G
S
Q
E
R
Q
R
Q
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517159
390
43415
P216
C
T
E
K
W
P
S
P
S
N
R
D
A
T
I
Chicken
Gallus gallus
Q9DDN6
385
43491
G215
S
E
K
W
P
G
E
G
Q
L
N
Y
G
T
I
Frog
Xenopus laevis
P34992
366
42234
P198
Y
V
C
L
E
D
F
P
E
D
K
F
R
L
S
Zebra Danio
Brachydanio rerio
NP_001034615
370
41772
G215
I
C
E
E
F
W
M
G
Q
E
K
E
R
L
A
Tiger Blowfish
Takifugu rubipres
NP_001098075
411
46956
P240
E
A
C
L
E
H
W
P
S
P
Q
H
R
L
I
Fruit Fly
Dros. melanogaster
P25931
464
53506
P266
Y
I
C
R
E
M
W
P
S
R
T
Q
E
Y
Y
Honey Bee
Apis mellifera
XP_001123033
393
45480
T199
R
K
I
F
S
S
I
T
S
I
L
Q
F
V
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
32.8
94.8
N.A.
90.2
89.4
N.A.
34
32.7
29.7
50.5
31.8
25.8
35.3
N.A.
N.A.
Protein Similarity:
100
99.4
55.3
96.4
N.A.
92.9
92.1
N.A.
52.8
54
51.8
64.3
49.6
44.1
54.9
N.A.
N.A.
P-Site Identity:
100
100
0
100
N.A.
93.3
93.3
N.A.
13.3
6.6
6.6
53.3
6.6
6.6
13.3
N.A.
N.A.
P-Site Similarity:
100
100
20
100
N.A.
100
100
N.A.
33.3
20
26.6
73.3
20
6.6
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
0
0
0
0
0
0
8
0
8
% A
% Cys:
8
47
24
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
8
0
0
0
8
0
8
0
0
0
% D
% Glu:
8
16
54
47
24
0
16
8
8
47
0
8
8
0
0
% E
% Phe:
0
0
0
8
47
0
8
0
0
0
0
8
8
0
0
% F
% Gly:
0
0
0
0
0
16
39
16
0
0
0
0
16
0
0
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
8
0
0
0
% H
% Ile:
8
8
8
0
0
0
8
0
0
8
8
0
0
0
39
% I
% Lys:
0
8
16
8
0
0
0
0
8
0
16
0
0
0
0
% K
% Leu:
39
0
0
16
0
0
0
0
0
8
8
0
0
24
31
% L
% Met:
0
0
0
0
0
8
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
8
8
0
0
0
0
% N
% Pro:
0
0
0
0
16
8
0
31
0
8
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
54
0
8
54
0
39
0
% Q
% Arg:
8
0
0
8
0
0
0
0
0
8
47
0
62
0
0
% R
% Ser:
8
0
0
0
8
8
8
39
31
8
0
0
0
0
8
% S
% Thr:
8
8
0
0
0
0
0
8
0
0
8
0
0
24
0
% T
% Val:
0
8
0
0
0
0
0
0
0
0
0
0
0
8
8
% V
% Trp:
0
0
0
16
8
47
16
0
0
0
0
0
0
0
0
% W
% Tyr:
16
0
0
0
0
0
0
0
0
0
0
16
0
8
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _