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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CTCF All Species: 31.82
Human Site: T265 Identified Species: 63.64
UniProt: P49711 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.27
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P49711 NP_006556.1 727 82785 T265 K K K G V K K T F Q C E L C S
Chimpanzee Pan troglodytes XP_001164059 699 79726 T265 K K K G V K K T F Q C E L C S
Rhesus Macaque Macaca mulatta XP_001088665 320 35776
Dog Lupus familis XP_536815 727 82839 T265 K K K G V K K T F Q C E L C S
Cat Felis silvestris
Mouse Mus musculus Q61164 736 83727 T265 K K K G V K K T F Q C E L C S
Rat Rattus norvegicus Q9R1D1 737 83861 T265 K K K G V K K T F Q C E L C S
Wallaby Macropus eugenll
Platypus Ornith. anatinus NP_001116829 728 82981 T265 K K K G V K K T F Q C E L C S
Chicken Gallus gallus Q08705 728 82810 T265 K K K G V K K T F Q C E L C S
Frog Xenopus laevis P08045 1350 155787 R777 R T H K T E K R Y P C N E C D
Zebra Danio Brachydanio rerio NP_001001844 798 89935 T305 K K K G V K K T F Q C E L C S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648109 818 93103 K293 N S N A S G H K Y S C P H C P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797592 939 102724 K439 E V G G A K K K T R Y V V P K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 92.7 43.7 99.5 N.A. 97.9 97.8 N.A. 95 93.4 20.7 72.6 N.A. 27.7 N.A. N.A. 27
Protein Similarity: 100 93.4 44 99.7 N.A. 98.2 98 N.A. 96.5 95 33 78.8 N.A. 43.5 N.A. N.A. 43.2
P-Site Identity: 100 100 0 100 N.A. 100 100 N.A. 100 100 20 100 N.A. 13.3 N.A. N.A. 20
P-Site Similarity: 100 100 0 100 N.A. 100 100 N.A. 100 100 40 100 N.A. 20 N.A. N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 9 9 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 84 0 0 84 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % D
% Glu: 9 0 0 0 0 9 0 0 0 0 0 67 9 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 67 0 0 0 0 0 0 % F
% Gly: 0 0 9 75 0 9 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 9 0 0 0 9 0 0 0 0 0 9 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 67 67 67 9 0 75 84 17 0 0 0 0 0 0 9 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 67 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 9 0 9 0 0 0 0 0 0 0 0 9 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 9 0 9 0 9 9 % P
% Gln: 0 0 0 0 0 0 0 0 0 67 0 0 0 0 0 % Q
% Arg: 9 0 0 0 0 0 0 9 0 9 0 0 0 0 0 % R
% Ser: 0 9 0 0 9 0 0 0 0 9 0 0 0 0 67 % S
% Thr: 0 9 0 0 9 0 0 67 9 0 0 0 0 0 0 % T
% Val: 0 9 0 0 67 0 0 0 0 0 0 9 9 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 17 0 9 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _