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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PSMB2 All Species: 38.18
Human Site: Y116 Identified Species: 56
UniProt: P49721 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P49721 NP_002785.1 201 22836 Y116 E H E G P A L Y Y M D Y L A A
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001109541 160 18000 P87 L A A L A K A P F A A H G Y G
Dog Lupus familis XP_532564 246 27881 Y161 E H E G P A L Y Y M D Y L A A
Cat Felis silvestris
Mouse Mus musculus Q9R1P3 201 22888 Y116 E H E G P A L Y Y M D Y L A A
Rat Rattus norvegicus P40307 201 22894 Y116 E H E G P A L Y Y M D Y L A A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508741 285 31024 Y200 E H E G P A L Y Y M D Y L A A
Chicken Gallus gallus XP_417777 201 22690 Y116 D H E G P A L Y Y M D Y L A A
Frog Xenopus laevis NP_001084761 199 22577 Y116 E H A G P S L Y Y M D Y L S A
Zebra Danio Brachydanio rerio NP_001002609 199 22568 Y116 E T D G P G L Y Y M D Y L S A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VQE5 210 23703 H118 A V E G P D L H Y I D S Y G A
Honey Bee Apis mellifera XP_393468 207 23613 Y116 D N T G P E L Y F I D Y L A S
Nematode Worm Caenorhab. elegans P91477 199 22530 L117 D K E D K A F L G S V D Y L A
Sea Urchin Strong. purpuratus XP_001178807 201 22910 F116 E T D G P C L F Y M D Y L G S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O23714 204 22522 Y115 D E S G A S L Y Y I D Y I A T
Baker's Yeast Sacchar. cerevisiae P22141 198 22498 L116 K K K N K P E L Y Q I D Y L G
Red Bread Mold Neurospora crassa Q9P6U7 203 22433 L116 P I T H K P S L Y W L D Y L A
Conservation
Percent
Protein Identity: 100 N.A. 79.5 80.8 N.A. 96.5 96 N.A. 62.8 86.5 82 81 N.A. 42.3 55.5 37.3 65.6
Protein Similarity: 100 N.A. 79.5 81.7 N.A. 99.5 99 N.A. 67.3 93 90.5 92 N.A. 64.7 73.9 63.6 83.5
P-Site Identity: 100 N.A. 0 100 N.A. 100 100 N.A. 100 93.3 80 73.3 N.A. 46.6 53.3 20 60
P-Site Similarity: 100 N.A. 13.3 100 N.A. 100 100 N.A. 100 100 93.3 86.6 N.A. 60 86.6 26.6 80
Percent
Protein Identity: N.A. N.A. N.A. 42.6 44.2 44.3
Protein Similarity: N.A. N.A. N.A. 62.2 64.6 64.5
P-Site Identity: N.A. N.A. N.A. 46.6 6.6 13.3
P-Site Similarity: N.A. N.A. N.A. 73.3 20 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 7 13 0 13 44 7 0 0 7 7 0 0 50 69 % A
% Cys: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % C
% Asp: 25 0 13 7 0 7 0 0 0 0 75 19 0 0 0 % D
% Glu: 50 7 50 0 0 7 7 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 7 7 13 0 0 0 0 0 0 % F
% Gly: 0 0 0 75 0 7 0 0 7 0 0 0 7 13 13 % G
% His: 0 44 0 7 0 0 0 7 0 0 0 7 0 0 0 % H
% Ile: 0 7 0 0 0 0 0 0 0 19 7 0 7 0 0 % I
% Lys: 7 13 7 0 19 7 0 0 0 0 0 0 0 0 0 % K
% Leu: 7 0 0 7 0 0 75 19 0 0 7 0 63 19 0 % L
% Met: 0 0 0 0 0 0 0 0 0 57 0 0 0 0 0 % M
% Asn: 0 7 0 7 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 7 0 0 0 69 13 0 7 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 7 0 0 13 7 0 0 7 0 7 0 13 13 % S
% Thr: 0 13 13 0 0 0 0 0 0 0 0 0 0 0 7 % T
% Val: 0 7 0 0 0 0 0 0 0 0 7 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 63 82 0 0 69 25 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _