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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCM2
All Species:
14.24
Human Site:
T9
Identified Species:
20.89
UniProt:
P49736
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49736
NP_004517.2
904
101896
T9
A
E
S
S
E
S
F
T
M
A
S
S
P
A
Q
Chimpanzee
Pan troglodytes
XP_001136482
895
100908
P14
Q
R
R
R
G
N
D
P
L
T
S
S
P
G
R
Rhesus Macaque
Macaca mulatta
XP_001099580
870
97929
T9
A
E
S
S
E
S
F
T
M
A
S
S
P
A
Q
Dog
Lupus familis
XP_541736
1001
113024
F106
L
L
E
S
S
E
S
F
I
V
A
S
S
P
A
Cat
Felis silvestris
Mouse
Mus musculus
P97310
904
102059
S9
A
E
S
S
E
S
L
S
A
S
S
P
A
R
Q
Rat
Rattus norvegicus
NP_001101343
905
102125
A10
E
S
S
E
S
F
S
A
A
S
S
P
A
P
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518428
911
102482
S15
S
E
P
S
N
A
T
S
S
P
A
A
R
Y
R
Chicken
Gallus gallus
NP_001006139
888
100332
A9
A
D
S
S
E
S
Q
A
A
V
T
S
P
V
R
Frog
Xenopus laevis
P55861
886
100243
N9
A
D
S
S
E
S
F
N
I
A
T
S
P
R
A
Zebra Danio
Brachydanio rerio
NP_775364
880
98286
N9
A
D
S
S
E
S
F
N
M
A
T
S
P
T
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P49735
887
100396
N10
N
P
S
S
P
P
P
N
T
P
S
D
A
A
E
Honey Bee
Apis mellifera
XP_395109
1005
114136
K116
E
I
T
S
V
V
D
K
L
Q
S
L
Y
F
L
Nematode Worm
Caenorhab. elegans
Q21902
759
84917
Sea Urchin
Strong. purpuratus
XP_001177558
884
100012
S10
D
R
T
S
E
P
F
S
D
P
T
S
P
A
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q43704
768
85163
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P29469
868
98761
S16
R
E
E
D
D
S
D
S
E
N
E
L
P
P
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
95.8
87.4
N.A.
95.5
96
N.A.
93.1
88.2
86.7
80.1
N.A.
63.9
58.4
26.7
73.4
Protein Similarity:
100
99
96.1
89.1
N.A.
97.7
98.3
N.A.
95.7
93.8
93
87.6
N.A.
79.3
73.5
43.2
86.5
P-Site Identity:
100
20
100
13.3
N.A.
53.3
20
N.A.
13.3
46.6
60
66.6
N.A.
26.6
13.3
0
40
P-Site Similarity:
100
40
100
26.6
N.A.
66.6
26.6
N.A.
53.3
66.6
80
86.6
N.A.
33.3
26.6
0
60
Percent
Protein Identity:
N.A.
30.3
N.A.
N.A.
41.9
N.A.
Protein Similarity:
N.A.
48.8
N.A.
N.A.
58.9
N.A.
P-Site Identity:
N.A.
0
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
0
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
38
0
0
0
0
7
0
13
19
25
13
7
19
25
19
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
19
0
7
7
0
19
0
7
0
0
7
0
0
0
% D
% Glu:
13
32
13
7
44
7
0
0
7
0
7
0
0
0
7
% E
% Phe:
0
0
0
0
0
7
32
7
0
0
0
0
0
7
0
% F
% Gly:
0
0
0
0
7
0
0
0
0
0
0
0
0
7
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
7
0
0
0
0
0
0
13
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% K
% Leu:
7
7
0
0
0
0
7
0
13
0
0
13
0
0
7
% L
% Met:
0
0
0
0
0
0
0
0
19
0
0
0
0
0
0
% M
% Asn:
7
0
0
0
7
7
0
19
0
7
0
0
0
0
0
% N
% Pro:
0
7
7
0
7
13
7
7
0
19
0
13
50
19
0
% P
% Gln:
7
0
0
0
0
0
7
0
0
7
0
0
0
0
25
% Q
% Arg:
7
13
7
7
0
0
0
0
0
0
0
0
7
13
25
% R
% Ser:
7
7
50
69
13
44
13
25
7
13
44
50
7
0
7
% S
% Thr:
0
0
13
0
0
0
7
13
7
7
25
0
0
7
0
% T
% Val:
0
0
0
0
7
7
0
0
0
13
0
0
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
7
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _