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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: COMP All Species: 8.18
Human Site: S28 Identified Species: 22.5
UniProt: P49747 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P49747 NP_000086.2 757 82860 S28 Q G Q S P L G S D L G P Q M L
Chimpanzee Pan troglodytes NP_001092035 757 82901 S28 Q G Q S P L G S D L G P Q M L
Rhesus Macaque Macaca mulatta XP_001115565 757 82553 S28 Q S Q I P S G S D L G P Q M L
Dog Lupus familis XP_533869 756 82387 A28 Q G Q I P L G A D L G P Q M L
Cat Felis silvestris
Mouse Mus musculus Q9R0G6 755 82334 A30 I P L G G D L A P Q M L R E L
Rat Rattus norvegicus P35444 755 82645 A30 I P L G G D L A P Q M L R E L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P35440 1178 131798 N244 S T E V N T I N E S T E I L H
Frog Xenopus laevis Q06441 955 104900 G215 S E A G Q Q T G D V S R Q L I
Zebra Danio Brachydanio rerio Q8JGW0 949 103972 L189 Q G K A Q E G L E E L K L A Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 96.1 93.1 N.A. 90.6 90.8 N.A. N.A. 35.4 56.6 54.3 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.7 97.3 95.1 N.A. 94 94.1 N.A. N.A. 45.4 65.5 65 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 80 86.6 N.A. 6.6 6.6 N.A. N.A. 0 13.3 20 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 80 93.3 N.A. 20 20 N.A. N.A. 26.6 33.3 40 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 12 12 0 0 0 34 0 0 0 0 0 12 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 23 0 0 56 0 0 0 0 0 0 % D
% Glu: 0 12 12 0 0 12 0 0 23 12 0 12 0 23 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 45 0 34 23 0 56 12 0 0 45 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12 % H
% Ile: 23 0 0 23 0 0 12 0 0 0 0 0 12 0 12 % I
% Lys: 0 0 12 0 0 0 0 0 0 0 0 12 0 0 0 % K
% Leu: 0 0 23 0 0 34 23 12 0 45 12 23 12 23 67 % L
% Met: 0 0 0 0 0 0 0 0 0 0 23 0 0 45 0 % M
% Asn: 0 0 0 0 12 0 0 12 0 0 0 0 0 0 0 % N
% Pro: 0 23 0 0 45 0 0 0 23 0 0 45 0 0 0 % P
% Gln: 56 0 45 0 23 12 0 0 0 23 0 0 56 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 12 23 0 0 % R
% Ser: 23 12 0 23 0 12 0 34 0 12 12 0 0 0 0 % S
% Thr: 0 12 0 0 0 12 12 0 0 0 12 0 0 0 0 % T
% Val: 0 0 0 12 0 0 0 0 0 12 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _