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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACOT2
All Species:
0
Human Site:
T185
Identified Species:
0
UniProt:
P49753
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49753
NP_006812.3
483
53218
T185
P
G
R
L
L
C
Q
T
R
H
E
R
Y
F
L
Chimpanzee
Pan troglodytes
XP_510048
483
53239
V185
P
G
R
L
L
C
R
V
R
H
E
R
Y
F
L
Rhesus Macaque
Macaca mulatta
XP_001091182
421
46346
R145
S
V
R
A
G
R
V
R
A
T
L
F
L
P
P
Dog
Lupus familis
XP_547892
445
48428
A154
A
G
R
L
L
G
R
A
L
H
A
R
H
F
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9QYR9
453
49634
A164
G
G
Q
R
L
A
H
A
V
H
E
R
H
F
L
Rat
Rattus norvegicus
O55171
453
49683
A164
G
G
Q
R
L
A
Q
A
V
H
E
R
H
F
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520078
421
46050
A146
L
R
E
G
K
V
R
A
T
L
F
L
P
P
G
Chicken
Gallus gallus
XP_426429
461
50969
A171
P
G
R
L
L
A
Q
A
Q
H
E
R
A
F
L
Frog
Xenopus laevis
NP_001084617
428
46458
G147
T
Q
E
R
G
F
I
G
A
G
V
S
R
I
P
Zebra Danio
Brachydanio rerio
XP_696711
513
56999
V215
D
D
K
V
L
A
K
V
T
N
E
R
H
C
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001169107
421
46466
A146
V
R
E
G
R
V
R
A
T
L
F
L
P
P
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
61.9
75.3
N.A.
68.7
70.1
N.A.
62.9
49.4
52.3
41.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.3
70.3
81.7
N.A.
79.9
79
N.A.
72.2
62.3
68.1
58.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
86.6
6.6
53.3
N.A.
46.6
46.6
N.A.
0
73.3
0
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
6.6
66.6
N.A.
60
66.6
N.A.
6.6
80
0
60
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
54.6
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
66.4
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
10
0
37
0
55
19
0
10
0
10
0
0
% A
% Cys:
0
0
0
0
0
19
0
0
0
0
0
0
0
10
0
% C
% Asp:
10
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
28
0
0
0
0
0
0
0
55
0
0
0
0
% E
% Phe:
0
0
0
0
0
10
0
0
0
0
19
10
0
55
0
% F
% Gly:
19
55
0
19
19
10
0
10
0
10
0
0
0
0
19
% G
% His:
0
0
0
0
0
0
10
0
0
55
0
0
37
0
0
% H
% Ile:
0
0
0
0
0
0
10
0
0
0
0
0
0
10
0
% I
% Lys:
0
0
10
0
10
0
10
0
0
0
0
0
0
0
0
% K
% Leu:
10
0
0
37
64
0
0
0
10
19
10
19
10
0
55
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% N
% Pro:
28
0
0
0
0
0
0
0
0
0
0
0
19
28
19
% P
% Gln:
0
10
19
0
0
0
28
0
10
0
0
0
0
0
0
% Q
% Arg:
0
19
46
28
10
10
37
10
19
0
0
64
10
0
0
% R
% Ser:
10
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% S
% Thr:
10
0
0
0
0
0
0
10
28
10
0
0
0
0
0
% T
% Val:
10
10
0
10
0
19
10
19
19
0
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
19
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _