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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACOT2
All Species:
4.55
Human Site:
Y351
Identified Species:
10
UniProt:
P49753
Number Species:
10
Phosphosite Substitution
Charge Score:
0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49753
NP_006812.3
483
53218
Y351
I
K
V
T
K
D
G
Y
A
D
I
V
D
V
L
Chimpanzee
Pan troglodytes
XP_510048
483
53239
Y351
I
K
V
T
K
D
G
Y
A
D
I
V
D
V
L
Rhesus Macaque
Macaca mulatta
XP_001091182
421
46346
E304
N
D
L
V
G
G
Y
E
N
S
S
M
I
P
V
Dog
Lupus familis
XP_547892
445
48428
L320
M
R
V
T
K
D
G
L
A
D
I
L
D
V
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9QYR9
453
49634
L330
V
K
M
T
K
D
G
L
L
D
V
V
E
A
L
Rat
Rattus norvegicus
O55171
453
49683
L330
V
K
M
T
K
D
G
L
L
D
V
V
E
A
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520078
421
46050
D304
N
S
P
L
E
E
P
D
T
Q
S
F
I
P
V
Chicken
Gallus gallus
XP_426429
461
50969
I337
A
R
V
Y
D
N
N
I
L
D
Y
S
D
I
A
Frog
Xenopus laevis
NP_001084617
428
46458
V305
I
K
F
P
Q
P
G
V
A
D
I
S
N
V
L
Zebra Danio
Brachydanio rerio
XP_696711
513
56999
L381
T
K
I
T
P
L
G
L
V
D
I
G
E
V
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001169107
421
46466
E304
N
D
A
V
G
G
C
E
N
P
S
M
I
P
I
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
61.9
75.3
N.A.
68.7
70.1
N.A.
62.9
49.4
52.3
41.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.3
70.3
81.7
N.A.
79.9
79
N.A.
72.2
62.3
68.1
58.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
0
73.3
N.A.
53.3
53.3
N.A.
0
20
53.3
40
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
20
93.3
N.A.
80
80
N.A.
20
40
66.6
60
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
54.6
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
66.4
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
0
0
0
0
0
37
0
0
0
0
19
10
% A
% Cys:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% C
% Asp:
0
19
0
0
10
46
0
10
0
73
0
0
37
0
0
% D
% Glu:
0
0
0
0
10
10
0
19
0
0
0
0
28
0
0
% E
% Phe:
0
0
10
0
0
0
0
0
0
0
0
10
0
0
0
% F
% Gly:
0
0
0
0
19
19
64
0
0
0
0
10
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
28
0
10
0
0
0
0
10
0
0
46
0
28
10
10
% I
% Lys:
0
55
0
0
46
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
10
10
0
10
0
37
28
0
0
10
0
0
55
% L
% Met:
10
0
19
0
0
0
0
0
0
0
0
19
0
0
10
% M
% Asn:
28
0
0
0
0
10
10
0
19
0
0
0
10
0
0
% N
% Pro:
0
0
10
10
10
10
10
0
0
10
0
0
0
28
0
% P
% Gln:
0
0
0
0
10
0
0
0
0
10
0
0
0
0
0
% Q
% Arg:
0
19
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
10
0
0
0
0
0
0
0
10
28
19
0
0
0
% S
% Thr:
10
0
0
55
0
0
0
0
10
0
0
0
0
0
0
% T
% Val:
19
0
37
19
0
0
0
10
10
0
19
37
0
46
19
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
10
19
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _