KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS41
All Species:
39.09
Human Site:
S176
Identified Species:
61.43
UniProt:
P49754
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49754
NP_055211.2
854
98566
S176
E
G
E
G
N
I
R
S
V
K
W
R
G
H
L
Chimpanzee
Pan troglodytes
XP_519057
852
98261
S176
E
G
E
G
N
I
R
S
V
K
W
R
G
H
L
Rhesus Macaque
Macaca mulatta
XP_001101460
879
101397
S201
E
G
E
G
N
I
R
S
V
K
W
R
G
H
L
Dog
Lupus familis
XP_533084
854
98472
S176
E
G
E
G
N
I
R
S
V
K
W
R
G
H
L
Cat
Felis silvestris
Mouse
Mus musculus
Q5KU39
853
98584
S175
E
G
E
G
N
I
R
S
V
K
W
R
G
H
L
Rat
Rattus norvegicus
NP_001100825
745
86357
V136
V
A
V
H
P
Q
F
V
R
S
S
C
K
Q
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512356
1286
146402
S607
E
G
E
G
N
I
R
S
V
K
W
Q
G
N
L
Chicken
Gallus gallus
NP_001012877
804
93396
C173
D
M
Y
P
C
S
L
C
W
K
D
N
L
T
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_691671
854
99073
S176
E
G
E
G
N
I
T
S
V
K
W
R
G
N
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001036416
841
96907
S178
S
V
E
G
S
V
L
S
I
C
W
H
G
N
F
Honey Bee
Apis mellifera
XP_624100
842
97559
S177
D
A
E
G
G
V
R
S
I
A
W
I
S
H
F
Nematode Worm
Caenorhab. elegans
Q19954
901
102561
F193
S
G
S
E
R
D
G
F
I
H
C
C
S
W
N
Sea Urchin
Strong. purpuratus
XP_797006
789
90527
S175
H
G
E
G
P
I
R
S
I
K
W
R
A
S
L
Poplar Tree
Populus trichocarpa
XP_002313553
952
107269
A188
S
G
E
G
P
I
H
A
V
K
W
R
T
S
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P93043
980
110260
S192
S
G
E
G
P
I
H
S
V
K
W
R
G
S
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
95.5
97.7
N.A.
97.1
83.3
N.A.
61.1
86.7
N.A.
82.1
N.A.
37.8
43
28.1
50.2
Protein Similarity:
100
99.7
96.2
99.3
N.A.
99.3
85.8
N.A.
63.4
90.9
N.A.
89.9
N.A.
58.2
65.4
50.5
69.2
P-Site Identity:
100
100
100
100
N.A.
100
0
N.A.
86.6
13.3
N.A.
86.6
N.A.
33.3
40
6.6
66.6
P-Site Similarity:
100
100
100
100
N.A.
100
0
N.A.
100
20
N.A.
93.3
N.A.
60
60
13.3
73.3
Percent
Protein Identity:
35.7
N.A.
N.A.
34.6
N.A.
N.A.
Protein Similarity:
54.5
N.A.
N.A.
52.8
N.A.
N.A.
P-Site Identity:
60
N.A.
N.A.
73.3
N.A.
N.A.
P-Site Similarity:
66.6
N.A.
N.A.
73.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
14
0
0
0
0
0
7
0
7
0
0
7
0
0
% A
% Cys:
0
0
0
0
7
0
0
7
0
7
7
14
0
0
0
% C
% Asp:
14
0
0
0
0
7
0
0
0
0
7
0
0
0
0
% D
% Glu:
47
0
80
7
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
7
7
0
0
0
0
0
0
20
% F
% Gly:
0
74
0
80
7
0
7
0
0
0
0
0
60
0
0
% G
% His:
7
0
0
7
0
0
14
0
0
7
0
7
0
40
0
% H
% Ile:
0
0
0
0
0
67
0
0
27
0
0
7
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
74
0
0
7
0
0
% K
% Leu:
0
0
0
0
0
0
14
0
0
0
0
0
7
0
74
% L
% Met:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
47
0
0
0
0
0
0
7
0
20
7
% N
% Pro:
0
0
0
7
27
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
7
0
0
0
0
0
7
0
7
0
% Q
% Arg:
0
0
0
0
7
0
54
0
7
0
0
60
0
0
0
% R
% Ser:
27
0
7
0
7
7
0
74
0
7
7
0
14
20
0
% S
% Thr:
0
0
0
0
0
0
7
0
0
0
0
0
7
7
0
% T
% Val:
7
7
7
0
0
14
0
7
60
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
7
0
80
0
0
7
0
% W
% Tyr:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _