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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: VPS41 All Species: 18.48
Human Site: S19 Identified Species: 29.05
UniProt: P49754 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.43
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P49754 NP_055211.2 854 98566 S19 L E E S T D E S E E E E S E E
Chimpanzee Pan troglodytes XP_519057 852 98261 S19 L E E S T D E S E E E E S E E
Rhesus Macaque Macaca mulatta XP_001101460 879 101397 L44 V E G R E G L L R E E E S E E
Dog Lupus familis XP_533084 854 98472 S19 L E E S T D E S E E E E S E E
Cat Felis silvestris
Mouse Mus musculus Q5KU39 853 98584 E18 S L E E S T D E S E E E S E E
Rat Rattus norvegicus NP_001100825 745 86357
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512356 1286 146402 S450 E G A Q A W E S E E E E S E E
Chicken Gallus gallus NP_001012877 804 93396 Y18 G T H Y G K V Y L L D V Q G N
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_691671 854 99073 S19 S E E S T D E S E E E D T E E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001036416 841 96907 D21 A D S I N E E D V E P K F K Y
Honey Bee Apis mellifera XP_624100 842 97559 S18 N N Q D D S D S E V D E V E P
Nematode Worm Caenorhab. elegans Q19954 901 102561 E30 D D V T F N T E D D D E P P L
Sea Urchin Strong. purpuratus XP_797006 789 90527 E19 D D D E N E E E A D E P K L K
Poplar Tree Populus trichocarpa XP_002313553 952 107269 E29 E D E E Q E E E E E E E Q E E
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P93043 980 110260 E33 E E E E E E E E N G D E A E E
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 95.5 97.7 N.A. 97.1 83.3 N.A. 61.1 86.7 N.A. 82.1 N.A. 37.8 43 28.1 50.2
Protein Similarity: 100 99.7 96.2 99.3 N.A. 99.3 85.8 N.A. 63.4 90.9 N.A. 89.9 N.A. 58.2 65.4 50.5 69.2
P-Site Identity: 100 100 46.6 100 N.A. 46.6 0 N.A. 60 0 N.A. 80 N.A. 13.3 26.6 6.6 13.3
P-Site Similarity: 100 100 53.3 100 N.A. 60 0 N.A. 60 6.6 N.A. 93.3 N.A. 40 46.6 46.6 46.6
Percent
Protein Identity: 35.7 N.A. N.A. 34.6 N.A. N.A.
Protein Similarity: 54.5 N.A. N.A. 52.8 N.A. N.A.
P-Site Identity: 53.3 N.A. N.A. 40 N.A. N.A.
P-Site Similarity: 66.6 N.A. N.A. 60 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 7 0 7 0 0 0 7 0 0 0 7 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 14 27 7 7 7 27 14 7 7 14 27 7 0 0 0 % D
% Glu: 20 40 47 27 14 27 60 34 47 60 60 67 0 67 60 % E
% Phe: 0 0 0 0 7 0 0 0 0 0 0 0 7 0 0 % F
% Gly: 7 7 7 0 7 7 0 0 0 7 0 0 0 7 0 % G
% His: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 7 0 0 0 0 0 7 7 7 7 % K
% Leu: 20 7 0 0 0 0 7 7 7 7 0 0 0 7 7 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 7 7 0 0 14 7 0 0 7 0 0 0 0 0 7 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 7 7 7 7 7 % P
% Gln: 0 0 7 7 7 0 0 0 0 0 0 0 14 0 0 % Q
% Arg: 0 0 0 7 0 0 0 0 7 0 0 0 0 0 0 % R
% Ser: 14 0 7 27 7 7 0 40 7 0 0 0 40 0 0 % S
% Thr: 0 7 0 7 27 7 7 0 0 0 0 0 7 0 0 % T
% Val: 7 0 7 0 0 0 7 0 7 7 0 7 7 0 0 % V
% Trp: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 7 0 0 0 7 0 0 0 0 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _