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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS41
All Species:
23.33
Human Site:
S249
Identified Species:
36.67
UniProt:
P49754
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49754
NP_055211.2
854
98566
S249
S
V
K
E
R
H
A
S
E
M
R
D
L
P
S
Chimpanzee
Pan troglodytes
XP_519057
852
98261
S249
S
V
K
E
R
H
A
S
E
M
R
D
L
P
S
Rhesus Macaque
Macaca mulatta
XP_001101460
879
101397
S274
S
V
K
E
R
H
A
S
E
M
R
D
L
P
S
Dog
Lupus familis
XP_533084
854
98472
S249
S
V
K
E
R
H
A
S
E
M
R
D
L
P
S
Cat
Felis silvestris
Mouse
Mus musculus
Q5KU39
853
98584
S248
S
V
K
E
R
H
A
S
E
M
R
D
L
P
S
Rat
Rattus norvegicus
NP_001100825
745
86357
R201
F
D
I
T
S
K
Q
R
I
T
N
V
P
R
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512356
1286
146402
G680
S
V
K
E
R
H
A
G
E
M
R
D
L
P
S
Chicken
Gallus gallus
NP_001012877
804
93396
K238
L
V
I
L
S
Y
V
K
E
I
S
E
K
T
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_691671
854
99073
T249
A
V
K
E
R
D
P
T
E
M
R
D
L
P
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001036416
841
96907
I252
V
I
R
K
R
N
S
I
E
A
S
T
G
N
L
Honey Bee
Apis mellifera
XP_624100
842
97559
T250
C
Q
I
R
K
R
S
T
Q
E
M
V
N
R
D
Nematode Worm
Caenorhab. elegans
Q19954
901
102561
D269
I
L
K
I
R
D
D
D
G
V
K
K
G
E
V
Sea Urchin
Strong. purpuratus
XP_797006
789
90527
I240
G
W
A
N
T
I
K
I
C
S
V
K
E
R
I
Poplar Tree
Populus trichocarpa
XP_002313553
952
107269
K261
S
I
R
A
N
E
Q
K
G
A
N
G
T
Y
R
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P93043
980
110260
Q265
S
I
K
S
D
Q
Q
Q
T
G
T
F
R
Q
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
95.5
97.7
N.A.
97.1
83.3
N.A.
61.1
86.7
N.A.
82.1
N.A.
37.8
43
28.1
50.2
Protein Similarity:
100
99.7
96.2
99.3
N.A.
99.3
85.8
N.A.
63.4
90.9
N.A.
89.9
N.A.
58.2
65.4
50.5
69.2
P-Site Identity:
100
100
100
100
N.A.
100
0
N.A.
93.3
13.3
N.A.
73.3
N.A.
13.3
0
13.3
0
P-Site Similarity:
100
100
100
100
N.A.
100
0
N.A.
93.3
33.3
N.A.
86.6
N.A.
46.6
26.6
33.3
0
Percent
Protein Identity:
35.7
N.A.
N.A.
34.6
N.A.
N.A.
Protein Similarity:
54.5
N.A.
N.A.
52.8
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
20
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
7
7
0
0
40
0
0
14
0
0
0
0
0
% A
% Cys:
7
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% C
% Asp:
0
7
0
0
7
14
7
7
0
0
0
47
0
0
14
% D
% Glu:
0
0
0
47
0
7
0
0
60
7
0
7
7
7
7
% E
% Phe:
7
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% F
% Gly:
7
0
0
0
0
0
0
7
14
7
0
7
14
0
0
% G
% His:
0
0
0
0
0
40
0
0
0
0
0
0
0
0
0
% H
% Ile:
7
20
20
7
0
7
0
14
7
7
0
0
0
0
14
% I
% Lys:
0
0
60
7
7
7
7
14
0
0
7
14
7
0
0
% K
% Leu:
7
7
0
7
0
0
0
0
0
0
0
0
47
0
7
% L
% Met:
0
0
0
0
0
0
0
0
0
47
7
0
0
0
0
% M
% Asn:
0
0
0
7
7
7
0
0
0
0
14
0
7
7
0
% N
% Pro:
0
0
0
0
0
0
7
0
0
0
0
0
7
47
0
% P
% Gln:
0
7
0
0
0
7
20
7
7
0
0
0
0
7
0
% Q
% Arg:
0
0
14
7
60
7
0
7
0
0
47
0
7
20
7
% R
% Ser:
54
0
0
7
14
0
14
34
0
7
14
0
0
0
47
% S
% Thr:
0
0
0
7
7
0
0
14
7
7
7
7
7
7
0
% T
% Val:
7
54
0
0
0
0
7
0
0
7
7
14
0
0
7
% V
% Trp:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
7
0
0
0
0
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _